IU Researchers Working Toward 'On-Demand' Organs

Posted: Updated:
IU Doctors Lester Smith, Burcin Ekser, Ping Lee IU Doctors Lester Smith, Burcin Ekser, Ping Lee
INDIANAPOLIS -

Indiana University School of Medicine researchers, backed by a $9 million private-sector partnership, are using genetically-engineered pig liver cells to 3D-print tissue that may one day be used for human organ and tissue transplants. The collaboration with Maryland-based Lung Biotechnology PBC was announced in early-May. Assistant Professor of Surgery Burcin Ekser, who leads the IUSM research lab dealing with cross-species transplantation, said artificially growing organs could eventually eliminate the often deadly wait for organs from humans.

In an interview with Business of Health Reporter Kylie Veleta in our Life Sciences INdiana enewsletter, Ekser said pairing with a private-sector partner is important. "Especially in science, the key is collaboration, and that will definitely bring us the outcomes we want," he said. The trade-off, Ekser adds, involves Lung Biotechnology PBC providing the funding and the IU team providing the knowledge, discoveries and technology -- which includes a type of 3D bioprinter that is found in only one other academic laboratory in the U.S. Both parties are pushing for a future with organs on-demand.

Researchers are printing tissue that is considered "scaffold-free" or able to stand up without the support of equipment. Currently, the IU team has created mouse-sized livers from the pig cells that are pumped with human blood. Over time, they will work to increase the size of their liver models.

Ekser says each success in research steadily moves the IU team forward.
Ekser says partnering with private companies is a critical strategy to advance academic research from the lab to the patient’s bedside.
  • Perspectives

    • Job Insights For The Third Quarter

      To provide accurate and timely employment forecasts for business leaders, Express Employment Professionals International Headquarters conducts an ongoing Job Insights survey to track quarterly hiring trends across a wide range of industries. Express surveyed business owners, decision makers, and human resource professionals about the overall hiring trends in their markets and how they impact their hiring decisions. Overall confidence remains high going into the second half of 2018.

    More

Subscribe

Name:
Company Name:
Email:
Confirm Email:
HTML
INside Edge
Morning Briefing
BigWigs & New Gigs
Life Sciences Indiana
Indiana Connections
INPower
Subscribe
Unsubscribe

Events



  • Most Popular Stories

    • Purdue Professor, Wife Indicted For Fraud

      A Purdue University professor and his wife have been indicted on federal fraud charges. U.S. Attorney Thomas Kirsch's office says Qingyou Han and Lu Shao are accused of hatching a scheme to defraud the National Science Foundation. 

    • Maureen Krauss (pictured left) is chief economic development officer at the Indy Chamber and Tom Leinbarger (pictured right) is chief executive officer at Cummins Inc.

      Indiana Businesses Fret Potential Trade War

      As a potential trade war looms over recently-imposed tariffs on China, Indiana businesses are expressing concern about the fallout. It is estimated that global trade supports more than 800,000 jobs in Indiana, many of those in the manufacturing and agriculture sectors. In 2016, Columbus-based Cummins Inc. sold more than 500,000 engines in China. Chief Executive Officer Tom Linebarger says the company's global footprint generates jobs and investment in Indiana.

    • The fund was first announced as part of Holcomb's Next Level Agenda. (Image courtesy of the state of Indiana.)

      Next Level Fund Makes First Investments

      Governor Eric Holcomb’s office says the Next Level Indiana Trust Fund has made its first two funding commitments. The fund, created by the Indiana General Assembly in 2017, has awarded a total of $21.5 million to Indianapolis-based High Alpha Capital and Colorado-based Foundry Group.

    • Fiat Chrysler Launching First-of-Its-Kind Clinic

      Fiat Chrysler Automobiles US LLC, which has five manufacturing facilities in Howard and Tipton counties, is partnering with Indianapolis-based St. Vincent Health on a new health and wellness center. FCA says it is the first domestic automaker to offer a near-site employee clinic. The "one-stop shop" is designed to deliver care to a workforce where some 40 percent do not have a primary care physician and often turn to emergency and urgent care facilities for primary...

    • and Lise Pace

      Bosma Enterprises Makes Hire, Promotion

      Bosma Enterprises has named Master Sgt. (Ret.) Jeffrey Mittman chief operating officer. He previously held positions at the Defense Finance and Accounting Services and National Industries for the Blind leveraging. Mittman served for 21 years in the United States Army, including four combat tours. Also, Lise Pace has been promoted to vice president of marketing and advocacy. She started with the organization as a volunteer in 2008.