Collaboration to Help with Organ Transplant Science

Posted: Updated:
IU Doctors Lester Smith, Burcin Ekser, Ping Lee IU Doctors Lester Smith, Burcin Ekser, Ping Lee
BLOOMINGTON -

Researchers at the Indiana University School of Medicine are closer to artificially growing organs, helped from a $9 million partnership with Maryland-based Lung Biotechnology. IU School of Medicine assistant professor of surgery Burcin Ekser and his team are trying to 3D print pig liver tissue from genetically-engineered cells.

The team would then use the printed tissue to expand new research for cross-species transplantation. Ekser was able to secure a four-year agreement with Lung Biotechnology. “This alliance with Lung Biotechnology will greatly enhance our ability to accomplish our ultimate goal of providing an unlimited supply of organs to save human lives,” Dr. Ekser said. “It’s my passion because I’m a transplant surgeon; I don’t want anyone to die while they’re waiting for a transplantable organ.”

Ekser says the research is fueled by the Cyfuse Regenova 3D bioprinter that is part of the school’s 3D Bioprinting Core. The school was one of the first in the country to get this bioprinter, and is now one of two academic institutions with the technology. Organ Procurement and Transplantation Network data indicates 110,000 people in the U.S. are waiting for a life-saving organ transplant, of whom 20 die each day. Dr. Ekser and the team have bioprinted genetically engineered pig cells and were able to supply and circulate fluid through the bioprinted pig liver model for a week. Ekser explains the research is important because it allows many different combinations of genetics to be quickly tested, which improves the probability of developing an organ patients won't reject. “That’s the reason that we do 3D bioprinting in xenotransplantation research,” he said. “It saves lives, saves money, saves time, saves effort… and it still gives us the answers we want.”

  • Perspectives

    • Sink or Swim: How to Stop Sabotaging New Hires

      You've jumped through the hiring hoops and emerged with some transformational talent. Before joining your company, Joe slashed costs and doubled revenue at his previous job, and Sue is known for building record-breaking teams and product launches. It should take them no time to produce similar results in your organization, right? In reality, Joe and Sue’s performances will hinge heavily on how you manage their post-hire assimilation: a cycle all new hires experience, lasting...

    More

Subscribe

Name:
Company Name:
Email:
Confirm Email:
HTML
INside Edge
Morning Briefing
BigWigs & New Gigs
Life Sciences Indiana
Indiana Connections
INPower
Subscribe
Unsubscribe

Events



  • Most Popular Stories

    • (photo courtesy Butler University)

      Aramark to End Operations at Butler

      Aramark Educational Services LLC has detailed plans to lay off 200 workers in Indianapolis. In a notice to the state, the company says the decision is the result of Butler University not renewing its contract to provide food services on the campus.

    • Metal Powder Products has Indiana operations in Noblesville and Campbellsburg.

      Manufacturer Growing Noblesville Operations

      Noblesville-based Metal Powder Products has announced plans to move a manufacturing division from Ohio to Hamilton County and add up to 80 jobs by 2020. The powder metallurgy product manufacturer says it will invest $1.5 million to increase production capacity in Indiana. The company currently employs more than 350 associates in its Noblesville and Washington County operations, and over 1,100 overall in the U.S. and China. MPP says it has already hired 51 employees as part of the...

    • Fishers Among Finalists For National Prize

      The city of Fishers is one of 12 finalists for the Robert Wood Johnson Foundation Culture of Health Prize. The award honors "communities that are bringing partners together around a shared commitment to health, opportunity, and equity."

    • Matt McIntyre is co-founder and executive director of Brackets For Good.

      Brackets For Good Launches New Program

      Indianapolis-based Brackets For Good Inc. is changing up its annual fundraising program. The sports-themed fundraising organization has launched Champ's Charity Challenge, in which users can fill out brackets for the NCAA men's college basketball tournament in the name of their charity of choice. The previous iteration of the program saw nonprofits competing in a tournament-style bracket of their own to see who could raise the most money. In an interview with Inside INdiana Business...

    • (file photo courtesy Schrader Real Estate and Auction Co.)

      Farmland Prices 'Remain Resilient'

      An auctioneer at Columbia City-based Schrader Real Estate and Auction Company says farmland prices “remain resilient" despite downward pressures."  R.D. Schrader cites mixed cropland prices on tillable land in 2018, stating that downward pressures include lower incomes, higher interest rates and the prospect of tariffs on farm goods.