WEBVTT

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>>I CAN'T CURE THE COMMON COLD.
AND I CAN'T CURE THIS, BUT I MAY
BE ABLE TO HELP SOMEBODY AVOID
THIS.

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>>GERRY: SUE STEWART ON WHY SHE
TOOK PART IN A RECENT IU SCHOOL
OF MEDICINE COVID-19 STUDY ON
CHILDREN AND ADULTS IN MARION

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COUNTY.
THE RESEARCH FOCUSED ON THOSE
WHO DO NOT DISPLAY ANY SYMPTOMS
OF THE DISEASE.

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MOST COVID-19 STUDIES ONLY KEY
IN ON ADULTS, BUT THE OUTCOMES
REVEALED WHY IT'S JUST AS
IMPORTANT TO INCLUDE

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ASYMPTOMATIC CHILDREN.
THE RESULTS ARE NOW IN, AND THEY
HELP ANSWER SOME BIG QUESTIONS
THAT PARENTS AND SCHOOL LEADERS

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HAVE BEEN WRESTLING WITH AS
STUDENTS HEAD BACK TO CLASS.
BUSINESS OF HEALTH REPORTER
KYLIE VELETA HAS MORE...

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>>KYLIE: THE RESULTS NOW SHOW
THAT ASYMPTOMATIC COVID-19
INFECTION IS POSSIBLE IN
CHILDREN UNDER 10, BUT IT IS A

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VERY LOW NUMBER.
AND THESE ASYMPTOMATIC KIDS MAY
NOT BE CONTAGIOUS.
THE INSIGHTS SHED LIGHT ON

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ISSUES SURROUNDING SCHOOL...
HERE TO HELP US SORT THROUGH
THOSE IS DR. JAMES WOOD, THE
STUDY'S CO-LEADER AND AN

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INFECTIOUS DISEASE DOCTOR AT
RILEY HOSPITAL FOR CHILDREN.
THANK YOU FOR BEING ON THE SHOW
TODAY.

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>> APPRECIATE YOU HAVING ME.
THIS STUDY IS THE FIRST OF ITS
KIND IN THE U.S. - WHAT MAKES IS
UNIQUE EVEN ON A NATIONAL SCALE?

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GERRY, BACK TO YOU.
>> SO WE WERE ABLE TO GO INTO
THE COMMUNITY AND TEST FAMILIES
INCLUDING YOUNG CHILDREN AS YOU

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MENTIONED WHICH WAS IMPORTANT TO
US.
WE REALLY WANTED TO FOCUS ON
KIDS UNDER TEN AND KIDS OF ALL

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AGES BECAUSE THAT'S AN AREA
WHERE THIS DISEASE HAS NOT BEEN
STUDIED ENOUGH IN OUR OPINION.
WE GO -- WE WERE ABLE TO TEST

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PEOPLE THAT WEREN'T HAVING TO
COME TO THE HOSPITAL OR WEREN'T
ABLE TO GO TO A STUDY SITE, FOR
EXAMPLE, SO GIVE US A LITTLE

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BETTER IDEA OF WHAT WAS GOING ON
IN THE COMMUNITY.
>> SO THE STUDY SAMPLED 511
PEOPLE IN MARION COUNTY.

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ONE TESTED POSITIVE FOR COVID-19
AND INTERESTINGLY IT WAS A SEVEN
YEAR OLD.
TELL US ABOUT THAT ONE CASE AND

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WHAT ARE WE LEARNING FROM THAT
ONE CASE IN THAT CHILD?
>> SO WE SHOWED THAT A
SEVEN-YEAR-OLD CHILD WAS

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POSITIVE AND THAT WAS KIND OF
THE FIRST OF ITS KIND THAT YOUNG
CHILDREN CAN HAVE THE VIRUS
ASYMPTOMATIC LEE.

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THAT IS SOMETHING WE FIGURED WAS
THE CASE BUT TO BE ABLE TO SHOW
IT IN A SCIENTIFIC STUDY IS
REALLY IMPORTANT AND I THINK AS

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THERE IS SO MUCH INFORMATION
THAT GOES OUT REALLY SHOWING
THAT IN A WELL DESIGNED STUDY IS
SUPER IMPORTANT SO WE WERE ABLE

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TO DO THAT.
AND WHAT WE WERE ALSO ABLE TO
SEE IS THE CHILD DIDN'T INFECT
OTHER PEOPLE IN HIS HOUSEHOLD.

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SO, AGAIN, WE CAN MAKE HUGE
CONCLUSIONS ABOUT HOW CONTAGIOUS
KIDS ARE FROM ONE CASE, BUT IT
GIVES US SOME OPTIMISM ABOUT

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GROWING RESEARCH THAT IS SHOWING
THAT MAYBE KIDS SYMPTOMS AREN'T
SUPER SPREADERS OR AS CONTAGIOUS
AS ONCE THOUGHT.

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>> RIGHT SO EVERY PARENT IS
THINKING ABOUT SCHOOL RIGHT NOW
SO WHAT ARE YOUR BIG TAKEAWAYS
FROM THE STUDY AS FAR AS SCHOOL

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CONCERNS?
>> I THINK SCHOOL IS REALLY A
REFLECTION OF THE COMMUNITY
WHERE IT IS.

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SO THE BIG TAKEAWAYS ARE
ESPECIALLY AT THAT TIME IN
MARION COUNTY'S NUMBERS WERE
RELATIVELY -- NUMBERS WERE FOR

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US WERE RELATIVELY LOW IN TERMS
OF ASYMPTOMATIC KIDS OR PEOPLE
THAT WERE INFECTED.
SO I GUESS WHAT WE CAN TAKE AWAY

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IS THAT I THINK THE GOAL IS
OBVIOUSLY TO GET BACK TO IN
PERSON CLASSES IN SCHOOL AND IN
AN AREA WHERE THE TRANSMISSION

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AND RATES ARE LOW I THINK THAT
WE CAN SAY MAY BE THE
ASYMPTOMATIC RATE IS FAIRLY LOW
AND WE CAN FEEL BETTER ABOUT

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CONTINUING TO DO SAFETY
PRECAUTIONS BUT GETTING BACK
INTO SCHOOLS WHICH IS OBVIOUSLY
EVERYBODY'S GOAL.

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>> ONE THING YOU MENTIONED IS
THROUGHOUT ALL OF THIS THE
PENDULUM HAS BEEN SWINGING.
IT WAS FIRST KIDS ARE SUPER

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SPREADERS AND THEN IT WAS
SWINGING TOWARD THEY ARE IMMUNE.
YOU THINK THE ANSWER MIGHT LIE
SOMEWHERE THERE IN BETWEEN?

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>> IT USUALLY DOES AND THAT'S
PROBABLY THE CASE FOR THIS AS
WELL.
MOST LIKELY KIDS ARE ABLE TO

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SPREAD THE VIRUS.
WE KNOW THAT, BUT PROBABLY NOT
TO THE EXTENT THAT FIRST THOUGHT
WHERE THEY WERE SUPER SPREADERS.

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VIRUSES KIDS DO SHED IT AND
SPREAD IT AND FOR A VARIETY OF
REASONS THAT IS NOT THE CASE FOR
COVID, BUT THAT DOESN'T MEAN

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THEY ARE IMMUNE SO BEING REALLY
CAUTIOUS AND KIND OF LISTENING
TO HEALTH OFFICIALS AND KEEP
THEM SOCIAL DISTANCING AND

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MASKING IS IMPORTANT, BUT I DO
THINK I'M OPTIMISTIC THAT THEY
ARE NOT THE SOURCE OF CRAZY
INFECTIONS AND WE CAN GIVE THEM

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RULES AND KEEP THEM IN SCHOOLS
OR GET THEM INTO SCHOOL IF THEY
ARE NOT ALREADY.
>> IT WAS INTERESTING THIS CHILD

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LIVING AND A HOUSE WITH FIVE
OTHER FAMILY MEMBERS AND NONE OF
THE FAMILY MEMBERS HAVE TESTED
POSITIVE AS YOU FOLLOW THEM UP.

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IF YOU ARE PLANNING A FOLLOW-UP
STUDY CAN'T TELL US ABOUT THAT
AND WHAT YOU HOPE TO LEARN FROM
THE FOLLOW-UP STUDY.

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>> SO WHAT WE WERE ABLE TO DO
FOR THIS STUDY IS LOOK AT ONE
POINT IN TIME WE LOOKED AT NASAL
SWABS AND WHO HAD THE VIRUS AT

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THAT POINT IN TIME.
BUT WE WANT TO KNOW IN THE
FOLLOW-UP STUDY WHO HAS BEEN
EXPOSED OR HAD INFECTION IN THE

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PAST AND THE WAY WE MEASURE THAT
IS THROUGH ANTIBODIES.
SO OUR FOLLOW-UP STUDY IS IN THE
SAME COHORT OF PEOPLE, BUT NOW

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TESTING ANTIBODIES TO SEE IF ANY
OF THOSE PEOPLE MAY HAVE BEEN
INFECTED OR EXPOSED TO THE VIRUS
AND SHOWED IMMUNITY TO THAT.

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SO THAT WILL GIVE US A BROADER
PICTURE OF EXACTLY THE LONGER
FRAME OF WHOSE HEAD THE
AFFECTION WITHOUT SYMPTOMS.

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>> YOU ARE SHARING THE RESULTS
WITH DECISION-MAKERS AT THE
STATE LEVEL.
THANK YOU SO MUCH FOR BEING ON

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THE SHOW IN HELPING US MAKE MORE
SENSE OF THE SCIENCE.
>> YOU ARE WELCOME.
HAVE A GOOD DAY.

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>>GERRY: THANKS, KYLIE!
ALSO MAKING HEADLINES FROM THE
IU SCHOOL OF MEDICINE...
IT WAS BEEN SELECTED AS A SITE

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FOR A COVID-10 VACCINE TRIAL.
THE ASTRAZENECA-SPONSORED PHASE
THREE TRIAL IS PART OF THE U.S.
DEPARTMENT OF HEALTH AND HUMAN

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SERVICES OPERATION WARP SPEED.
IT'S A PARTNERSHIP WITH OXFORD
UNIVERSITY AND IS MOVING FORWARD
WITH ITS LATE-STAGE CLINICAL

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TRIAL FOR A VACCINE KNOWN AS AZD
12-22.
THIS PHASE THREE CLINICAL TRIAL
IS THE LAST REQUIRED STAGE OF

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STUDY BEFORE THE POTENTIAL
VACCINE CAN BE APPROVED BY THE
FOOD AND DRUG ADMINISTRATION FOR
WIDESPREAD PUBLIC USE.

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IT IS ONE OF ONLY FOUR VACCINES
IN PHASE III TESTING FOR THE
PREVENTION OF COVID-19 IN THE
UNITED STATES.

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RESEARCHERS PLAN TO ENROLL A
TOTAL OF 30,000 PARTICIPANTS AT
81 DIFFERENT SITES AROUND THE
UNITED STATES FOR THIS STUDY.

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PEOPLE FROM ACROSS THE STATE ARE
INVITED TO PARTICIPATE, BUT
VOLUNTEERS WILL NEED TO TRAVEL
TO INDIANAPOLIS TO RECEIVE TWO

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DOSES OF THE VACCINE OR PLACEBO,
AS WELL AS ATTEND FOLLOW-UP
VISITS.
VOLUNTEERS WILL BE COMPENSATED

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FOR THEIR TIME AND