More than $1 million in grants will boost efforts by two IUPUI researchers to study the effects of exercise on chronic health issues. The National Institutes of Health funds will support examinations of what physical activity does to decrease skeletal muscle loss in animals with chronic kidney disease as well as potentially offsetting conditions like osteoporosis.

Both researchers are assistant professors of physical therapy in the School of Health and Rehabilitation Sciences. 

IUPUI says Keith Avin's nearly $675,000 grant could lead to findings that advance efforts to help the estimated 20 million Americans with chronic kidney disease who suffer symptoms such as muscle loss, muscle weakness and reduced mobility.

William Thompson's work involves studying the role exercise plays in whether bone marrow stem cells become bone cells or fat cells. The NIH is pledging more than $460,000 toward the research.

You can read more about the grants and research details by clicking here.