Leaders of the Komen Tissue Bank at the Indiana University Simon Cancer, the only repository in the world for normal breast tissue, say the organization is taking its data “to a whole new level.”

The rampant spread of coronavirus in China is a reminder of a frustrating limitation of modern science: researchers have yet to uncover how to kill viruses.

Her older brother as her muse, recent Purdue University alumna Hannah Ferrill is hopeful children with Down syndrome will soon be playing with the toy she designed with them in mind.

The mayor of Noblesville says today's announcement that India-based Panacea Medical Technologies Inc. will set up operations in the Hamilton County city is just the beginning of things to come. The company plans to invest nearly $12 million to...

A medical tech and life sciences company based in India has announced plans to establish operations in central Indiana. Panacea Medical Technologies Inc. says it will invest nearly $12 million to build its North American headquarters in Noblesville and...

Two Hoosier research powerhouses are joining forces. Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) and Purdue University have announced a four-year research agreement, which the university says will involve collaboration and training talent...

An assistant professor of biology at Butler University is conducting research that could one day play a role in helping to find a treatment for coronavirus. Chris Stobart is a virologist who looks for new behaviors in viruses. He’s currently focusing...

Four Indiana life sciences startups are among a group of semifinalists for the 2020 bioLOGIC Innovation Awards. Online voting begins this weekend to select four finalists to compete in a $50,000 pitch contest in Louisville next month.

The $38 million manufacturing plant—perhaps the largest life sciences investment in years by a new-to-Indiana company—will make Abbott’s MitraClip, a heart device that is “fueling new growth for the company.”

About a dozen Hoosier pet dogs are considered success stories after undergoing an experimental therapy for bladder cancer being developed at Purdue University.

Boosted by a $2 million grant, researchers at the Regenstrief Institute in Indianapolis will begin scientifically testing what many people instinctively know already: music just makes them feel better.

A Purdue University-affiliated startup is tackling a problem it says could help some 9 million people in the U.S. with swallowing disorders.

An artificial intelligence firm specializing in the life sciences just received a $500,000 investment from Purdue Research Foundation’s Foundry Investment Fund.
PhysIQ is a Purdue-affiliated company founded by Gary Conkright, a graduate in...

The Indiana University School of Medicine is marking another record year of funding growth. The school says it received more than $189 million in research funding from the National Institutes of Health in the 2019 federal fiscal year, an increase of...

A medical device company in Brown County is developing technology to help against bed sores. Wave Therapeutics, a subsidiary of Bussert Medical Inc. in Nashville, has raised $500,000 from investors to further develop the device, which has...

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) and California-based Strateos Inc. have unveiled a robotic laboratory in San Diego. The pharmaceutical company says the Lilly Life Sciences Studio lab is designed to accelerate the drug discovery process.

A biopharmaceutical company is diminishing its presence in Indiana. Assembly Biosciences Inc. (Nasdaq: ASMB) has relocated its corporate headquarters from Carmel to the San Francisco Bay Area.

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced plans to acquire a California biopharmaceutical company. The all-cash deal for Dermira Inc. (Nasdaq: DERM) is valued at approximately $1.1 billion.

Fishers-based The Clarke Companies is expanding its portfolio of life sciences-focused businesses with the acquisition of Covex LLC, an information technologies firm in Pennsylvania. The company says the acquisition helps it to better serve...

The U.S. District Court for the Southern District of Indiana has vacated a $3 million judgment against Bloomington-based Cook Medical. The company had been sued by a Georgia woman who claimed an intravenous filter made by Cook deteriorated inside...

A top researcher at the Indiana University School of Medicine in Indianapolis is leaving. Anantha Shekhar, associate vice president of research and university clinical affairs, has been named the senior vice chancellor for the health sciences at...

An Indianapolis-based tech company is expanding its touring industry networking event on a global scale. Greenlight Guru, which provides a quality management software platform for medical devices companies, says its True Quality Roadshow will make a...

Carmel-based MBX Biosciences Inc. has announced co-founder Kent Hawryluk as its next president and chief executive officer. In addition to his new roles, Hawryluk is a member of the preclinical-stage biotechnology company's board of directors.

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has received another favorable ruling regarding the patent for its vitamin regimen Alimta. The ruling from the U.S. District Court for the Southern District of Indiana is the latest in a string of...

West Lafayette-based Bioanalytical Systems Inc. (Nasdaq: BASI) is reporting a fiscal full-year net loss of $790 million, compared to a loss of $194 million the previous year. Chief Executive Officer Robert Leasure says, however, the company started to...

A newly-established medical device company has announced plans to set up operations in Whitley County. The Whitley County Economic Development Corp. says Mach Medical will invest nearly $14 million to establish a manufacturing and...

A Fort Wayne-based medical device manufacturer has closed a $2 million round of funding. BioPoly LLC says the private equity financing will be used to bring products to the U.S. market and launch a product line extension in Europe.

The small town of Bunker Hill will soon be home to a cutting-edge 140-ton, three-story tall machine—only the second in the U.S.—that is revolutionizing how certain diagnostic tools and therapies are delivered in healthcare.

Electronic health information exchange (HIE) has come a long way since its inception in the late 1990s when it seemed like a “crazy, out-of-the-box idea,” says one Hoosier health IT leader.

The Centers for Disease Control and Prevention says people with hemophilia should rely on Hemophilia Treatment Centers (HTCs) to ensure they’re receiving the best care for the medical condition—and Indiana is home to one of the largest HTCs in the nation.

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced its 2020 financial guidance. The pharmaceutical company says the guidance is highlighted by volume-based revenue growth and improving productivity.

The Indiana University School of Medicine is touting a major discovery in the fight against breast cancer. The school says researchers have discovered how to predict whether triple negative breast cancer will recur and which women are likely to remain...

Texas-based LifeScience Logistics has announced plans to grow its central Indiana operations. The company says it will invest $15 million to build a 280,000-square-foot storage and distribution facility in Whitestown and create 50 jobs.

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced the winner of its first digital health open innovation challenge. The nationwide competition sought to find digital health solutions aimed at transforming care for Inflammatory Bowel Disease.

A team of recent University of Notre Dame alumni—and soon-to-be graduates—is creating a high-tech prosthetic hand they believe will change the lives of amputees.

atients who have undergone a diabetes-related amputation currently face a terrifying prognosis: only 50 percent survive one year after losing the limb, says University of Notre Dame Chemistry and Biochemistry research professor Dr. Mayland Chang.

The training of tomorrow’s scientists is getting a nearly $200 million shot in the arm as Hoosier universities break ground on building projects aimed at undergraduate science education.

INDIANAPOLIS -- Indianapolis-based Eli Lilly and Co. (NYSE: LLY) is further growing its Indianapolis operations. The pharmaceutical giant has announced plans to invest $400 million in its manufacturing facilities at the...

INDIANAPOLIS -- A coalition of life sciences organizations and Hoosier universities has launched a mentorship program designed to "add more power to the entrepreneurial environment." BioCrossroads, Indiana's life sciences initiative...

WEST LAFAYETTE, Ind. -- West Lafayette-based Bioanalytical Systems Inc. (Nasdaq: BASI) has launched a rebranded contract research services business, Inotiv. The company says the rebrand represents the union of several acquisitions it has made over the past two years.

Bunker Hill, a town of about 900 people near the Grissom Air Reserve Base in Miami County, has landed a multi-million-dollar life sciences company, which could create up to 40 high paying jobs by the end of 2022. Phoenix-based Arizona Isotopes Research Corp. has announced plans to establish research and production operations in north central Indiana.

NOBLESVILLE, Ind. -- A medical device manufacturer in Noblesville is growing. The Indiana Economic Development Corp. says Nexxt Spine LLC, which designs and manufactures spinal implants and instrumentation, plans to invest nearly $9 million to double the size of its headquarters and create up to 36 jobs by the end of 2022. The company will purchase, renovate and equip and industrial building in the Saxony Corporate Campus. The renovations are set to begin in June 2020 and be complete...

Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) is reporting third-quarter net earnings of $432 million, compared to $162 million during the same period last year. Zimmer Biomet is an orthopedic device maker in Kosciusko County.

A battle plan—with data as the driving force—is being created in Fort Wayne to combat Indiana’s high infant mortality rate, the seventh highest in the country. Governor Eric Holcomb named Allen County among 20 “high priority” counties to launch OB Navigator, a statewide initiative to build better health for Hoosier mothers and babies. 

For people with Type 1 diabetes, a life free from injections and 24/7 monitoring of their blood glucose levels may seem only a fantasy, but an Indianapolis-based biotech company believes relief could come in pill form. 

Parkinson’s disease is a grim diagnosis; it’s typically not detected until a person exhibits the characteristic tremors, when it’s progressed too far to slow the condition. West Lafayette-based Tymora Analytical Operations envisions a routine urine test that would spot Parkinson’s early, when medication and other strategies can slow its progression. 

Indiana’s might in neuroscience research is undeniable, says Indianapolis neuroscientist Dr. Bruce Lamb, adding that “it’s striking to me how fast it’s all moving—Indiana very quickly becoming a national leader in neuroscience.” 

Executives from Franklin-based B2S Life Sciences LLC will be joined by state and city officials Wednesday to celebrate its $1.5 million expansion project. The company announced plans last year to grow its Johnson County, operations by renovating its facility and adding 9,000 square feet of laboratory space. 

A West Lafayette-based pharmaceutical research company, based at Purdue Research Park, has changed its name to better reflect the company’s focus. Purdue GMP Center Inc. is now operating as Parsolex GMP Center Inc. It’s doing business as Parsolex. 

Global healthcare company Abbott Laboratories (NYSE: ABT) has announced plans to invest $37 million in a new facility in Westfield, creating approximately 450 new jobs. The 120,000-square-foot facility will be built in the Northpoint Industrial Park along U.S. 31 in Westfield. The Chicago-based medical device maker says the facility will manufacture its MitraClip transcatheter mitral valve repair system.  Construction is set to begin later this year. The company says hiring...

Roche Diagnostics Corp. has selected Matthew Sause as president and chief executive officer of its North America operations, headquartered in Indianapolis. Sause previously served as senior vice president and head of global commercial product strategy for California-based Gilead Sciences Inc. (Nasdaq: GILD).

Virginia-based LifeNet Health says it intends to expand its presence in Plainfield with the addition of more than 100 jobs. The biomedical firm says it is investing more than $18 million as it expands in Indiana. LifeNet Health’s 70,000-square-foot biologics logistics center is already operational and currently employs 45 people. The plan is to grow its staff by up to 127 employees by the end of 2023. Elaine Bedel, president of the Indiana Economic Development...

State and local officials will Tuesday make an economic development announcement in Plainfield. Few details are available, however the Indiana Economic Development Corp. says executives from Virginia-based nonprofit LifeNet Health will be in attendance.

Seven life science organizations in Indiana are collaborating on a one-stop shop for information, called INscience. BioCrossroads, Cook Regentec, Corteva Agriscience, Eli Lilly and Co., Indiana Biosciences Research Institute, Indiana Clinical and Translational Sciences Insititute and Roche Diagnostics have teamed to educate and engage Indiana's $78 billion life sciences economy. 

The Purdue Foundry is set to unveil its first cohort for the Double Down Experiment, which includes nine high growth businesses the organization says are ready to reach the next level. The Purdue Foundry is co-hosting The Big Show, to showcase the innovators and business builders selected for the program.

An Indiana company that specializes in wheelchair lifts and van conversions so they’re wheelchair-accessible has announced plans to increase the number of workers with disabilities. BraunAbility made that announcement as it opened its new global headquarters in Carmel. 

The National Institutes of Health has awarded a $36 million grant to the IU School of Medicine to launch a drug discovery center focused on accelerating the development of treatments for Alzheimer's disease. The center is part of a strategic partnership with the Purdue Institute for Drug Discovery, and IU says the partnership is one of only two multi-institution teams in the country selected for a new federal program designed to grow the drug development pipeline for the disease.

Indiana's life sciences initiative is launching a new competition designed to help solve two health issues facing Hoosiers: diabetes and opioid abuse. BioCrossroads says the DataX BioInnovation Challenge was created to "intersect life sciences and data research," giving innovators the opportunity to use data sets to identify and investigate hypotheses to improve the health issues. The winning team or teams could receive up to $50,000 cash. In an interview with...

Today at the Indiana Life Sciences Summit, BioCrossroads’ Board of Directors named Dr. Clem J. McDonald recipient of the 2019 August M. Watanabe Life Sciences Champion of the Year Award. The prestigious honor named in tribute to BioCrossroads’ late Chairman August Watanabe, was given to Dr. McDonald for his unprecedented impact on health IT and digital health in Indiana and abroad. 

An orthopedic medical device company in central Indiana that has been quietly growing for the last two decades admits “we’re a big secret, but we don’t mean to be.” Noblesville-based Nexxt Spine has launched its latest product and is aiming to “spread the word” about its growing device portfolio. 

Studies have already uncovered the dangerous impact on babies when mothers have opioid abuse disorder, and other research has examined the use of opioids to treat opioid abuse disorder. However, Indiana University scientists are now addressing an unanswered question: what about expectant mothers who are prescribed the medications to treat pain? 

There is much excitement surrounding microbes in life sciences research—and for good reason. Dr. Rajesh Perianayagam says scientists have discovered 17 microbiome-related cures and therapies for an equal number of diseases. But this flurry of excitement—and the recent proliferation of genetic sequencing technology—is drowning scientists in data. 

The first company to spin out of Indianapolis-based Cook Regentec has secured $5 million in growth capital. Sexton Biotechnologies, also based in Indy, says it will use the funding to expand and scale the commercialization of its portfolio.

National and global leaders in the worlds of agriculture, technology, and science have closed out the 2019 Forbes Ag Tech Summit in Indianapolis, now in its second year in the state. The event gathered industry leaders and entrepreneurs who are looking for answers to the challenges of growing and producing food. The two-day summit, hosted by AgriNovus Indiana, addressed food animal health, protein and crops.

The U.S. Food and Drug Administration has awarded clearance to Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) for a meniscal repair device. The medical device manufacturer says the device, known as JuggerStitch, will be available in the U.S. market.

Indianapolis-based Toralgen Inc. says it has raised nearly $2 million in seed funding for what the company calls its transformative drug delivery tool. The biotechnology firm is attempting to commercialize a nanopill system, a microscopic-sized dose of medication, for diabetes control and other diseases.

Carmel-based MBX Biosciences Inc. has received a $500,000 investment from the Indiana University Philanthropic Venture Fund. The medical biotech firm, whose founders include high-profile inventor Dr. Richard DiMarchi, has developed therapeutics to treat endocrine diseases.

A California-based shareholder rights litigation firm is investigating Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH). The Schall Law Firm says its investigation, being conducted on behalf of Zimmer Biomet investors, is related to claims of failing to disclose information pertinent to investors.

An IUPUI psychologist has been awarded a nearly $2 million grant from the National Cancer Institute for her research to help cancer patients, in advanced stages of the disease, to still find quality of life while accepting the eventual outcome. The university says Professor Catherine Mosher is investigating a novel acceptance-based approach of facing the disease, while fighting the fatigue and other systems seen in late-stage cancer patients.

An Indianapolis-based tech company and a research powerhouse are combining forces to put health at Hoosiers’ fingertips with a new mobile app. While the market may seem saturated with health apps, the creators of LIFE Extend—tech startup LifeOmic and the Indiana Clinical and Translational Sciences Institute (CTSI)—believe the new tool is one-of-a-kind. 

Micropulse Chief Executive Officer Brian Emerick says any other manufacturer can make the same orthopedic devices as his company; instead, the blueprint for success at the Columbia City-based contract manufacturer centers on culture. Micropulse, which started 31 years ago in his garage, has produced steady, incremental growth “organically, by word of mouth and brand,” and Emerick believes the strategy is delivering again with a $6.8 million expansion. 

Focusing on “the deadliest animal on Earth,” an Indiana University biologist is trying to cripple a dangerous killer: the mosquito. While mostly just a nuisance swatted away in the U.S., IU Biology Associate Professor Dr. Irene Newton says, “you can think of the mosquito as the apex predator on the planet, because the diseases it carries kill so many people.” 

Among hospital-acquired infections, MRSA gets most of the attention, says a Purdue University researcher; this leaves the second most common hospital-acquired infection lurking in the shadows. Vancomycin-resistant enterococci (VRE), similar to MRSA, is characterized by its antibiotic resistance, making it especially dangerous and difficult to treat. 

Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) has entered into an agreement with Bayer AG (ETR: BAYN) to acquire its animal health business in a deal valued at $7.6 billion. If approved, it would double Elanco’s Companion Animal business and create the second-largest animal health company by revenue. “Joining Elanco and Bayer Animal Health strengthens and accelerates our IPP strategy, transforms our portfolio with the addition of well-known pet brands, brings...

Noblesville-based Nexxt Spine LLC has received clearance from the U.S. Food and Drug Administration for its NEXXT MATRIXX Stand Alone Cervical System. The system is a "stand-alone anterior cervical interbody fusion system" intended to be used for treatment of degenerative disc disease.  

A new report from Bloomberg says an agreement between Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) and Germany-based Bayer AG could be announced as soon as next week. The news service reported Wednesday the two companies are looking to announce a deal involving Bayer's animal health unit around the time of Elanco's earnings release, which will take place Tuesday. Bloomberg, citing sources who asked to not be identified due to the private nature of the discussions...

A Whitley County-based medical device manufacturer is expanding its northeast Indiana operation and adding about two dozen jobs. Columbia City-based Micropulse Inc., says it is investing $6.8 million to expand, equip and better utilize its 160,000-square-foot facility. 

A medical device manufacturer in Whitley County is growing its operations. Micropulse Inc. has announced plans to invest nearly $7 million to expand its Columbia City facility and create up to 25 jobs by the end of 2020. The Indiana Economic Development Corp. says the company will add 15,000 square feet to its 160,000-square-foot facility, while also renovating 3,000 square feet of existing space to make it "better suited for growth." The company says the project will allow...

Farmers spend big bucks on fertilizer; a West Lafayette-based startup says it’s typically the third highest per-acre expense. Farmers rely on soil sampling—typically done by hand—to determine how much fertilizer to apply to their fields and where to spray it. 

Indianapolis-based Exelead specializes in small, but it means big business. The contract development and manufacturing company makes the final formulations for drugs that treat rare and small populations; “large-scale pharmaceutical companies wouldn’t touch some of the products we manufacture, because of scale,” says Chief Executive Officer John Rigg. 

Urinary tract infections (UTIs) are one of the most common infections in elderly and children, yet these two groups may also be unable to alert caregivers when they have symptoms. A Purdue University researcher has developed a tool to safeguard against children and elderly suffering from the elusive infections. 

An innovation is brewing in Fort Wayne for craft beer businesses or even hobbyists making their ale at home. Two companies are combining their expertise to create a “kit” to grow hops at home or on small acreage. 

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) is reporting second quarter net income of $1.3 billion, compared to a net loss of $260 million during the same period last year. The company says the results were driven, in part, by several U.S. Food and Drug Administration approvals.

Greenfield-based Elanco Animal Health Inc.(NYSE: ELAN) completed its purchase Thursday of Aratana Therapeutics (Nasdaq: PETX), a pet therapeutics company located near Kansas City. As Inside INdiana Business first reported Tuesday Aratana shareholders voted overwhelmingly in favor of the $245 million deal. 

Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) is one step closer to adding to its portfolio. Shareholders of Aratana Therapeutics Inc. (Nasdaq: PETX), voted overwhelmingly in favor of proposed $245 million purchase by Elanco.

Just four months after finalizing its split with Eli Lilly and Co. (NYSE: LLY), Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) is reportedly in talks with Germany-based Bayer over a possible merger with its animal health division. According to Reuters news service, the two companies are working with banks to ensure any merger would receive regulatory approval. Elanco was part of Lilly for six decades until it was spun off into an independent public company last fall.

Eli Lilly and Company (NYSE: LLY) has announced several changes to the company's executive committee. Mike Harrington is retiring from his positions of senior vice president and general counsel at the end of the year. Senior vice president and president of Lilly Bio-medicines, Christi Shaw, is leaving Lilly at the end of August, and will be succeeded by current president and general manager of Lilly Japan, Patrick Jonsson. 

A team of researchers from the Indiana University School of Medicine in Indianapolis will Tuesday begin the second phase of an experiment heading to space. The research project will study the effect of spaceflight on osteoblast cells, which are essential to bone development, as well as the effects of certain drugs on bone healing. Melissa Kacena, director of basic and translational research at the school, is leading the effort in collaboration with NASA and the U.S. Army. The first...

State and local officials will Friday join executives from New Jersey-based Catalent Inc. (NYSE: CTLT) to break ground on a new drug product manufacturing facility in Bloomington. The project is part of a $100 million expansion announced in January that is expected to create up to 200 jobs by the end of 2024.

Caring for a child with type 1 diabetes is a heavy burden for parents and not limited to the daily grind of tracking blood sugar and dosing insulin; for many, the weight of worry is far greater. 

Twenty-six extremely fragile crates—including one that must remain in a vacuum—will soon be shipped from the Netherlands. Their destination: the Purdue University campus, where the contents will be pieced together to form a state-of-the-art $9 million microscope. 

A quick glance at Annie Ostojic’s Facebook page is evidence that she isn’t your average teenager—it sings of impressive scientific conquests: pictures of her when she was named to Forbes 30 Under 30 (when she was only 15), World’s 50 Smartest Teens, and shows Ostojic under the spotlight, presenting centerstage at national conferences. 

Immunotherapy is described as a revolution, uncovering cures for a variety of cancers. Most of the progress has benefited adults battling the disease, but a recent $4.1 million Cancer Moonshot grant is helping a Hoosier researcher extend the power of immunotherapy to children and adolescents. 

The incoming chief executive officer of BioCrossroads says she hopes to continue the growth Indiana's life sciences sector. Patty Martin, who was announced today as the new president and CEO of the state's life sciences initiative, comes with more than two decades of experience at Indianapolis-based Eli Lilly and Co. (NYSE: LLY). She says she initially plans to spend time getting to know many of the people involved in the sector from the corporate, academic and philanthropic levels...

After a national search, BioCrossroads has announced Patty Martin will become the life science initiative's next president and chief executive officer. Martin, who most recently served as chief operating officer for Lilly Diabetes, will begin her new role Monday. She will become just the third CEO in the organization's 17-year history, and succeeds David Johnson, who in December announced plans to step down from the role to serve as president and CEO of the...

Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) has announced a succession plan for retiring Executive Vice President and Chief Financial Officer Daniel Florin. He is set to retire on July 1 and the company has announced Suketu Upadhyay has been appointed to succeed Florin. The company says Florin will continue with the company in an advisory capacity to ensure a successful transition. 

As Franklin College President Thomas Minar prepares to step down at the end of the 2019-2020 academic year, he says the school is well-prepared to leverage its science heritage well into the future. During an interview on Inside INdiana Business With Gerry Dick, he says the school's new $17 million Health Science Center features "the most modern science facilities imaginable." Minar, who has been the school's president since July 2015, says a fundraising campaigning topping...

A Warsaw-based medical device manufacturer has landed a key approval. Ignite Orthopedics LLC has received FDA clearance to market its Radial Head Arthroplasty System, marking what the company says is a "significant milestone" in its mission.

It isn’t easy doing chemistry in a panicked state, but that’s exactly what a person must accomplish when using current hypoglycemia rescue kits, says Dr. Elizabeth Topp, a Purdue University industrial and physical pharmacy professor. 

A Fishers-based company says it’s creating a replacement for “one of the most universally-hated products” among surgical patients. Although detested, intermittent pneumatic compression (IPC) devices are required after the vast majority of surgeries; worn on the calf from knee to ankle, the sleeves squeeze the legs every 60 seconds, increasing blood flow to prevent clots due to immobility.

Posttraumatic stress disorder (PTSD) may seem an obvious diagnosis for combat veterans, but the condition can lurk in dark corners for others not commonly screened for it, such as victims of abuse, violence or accidents. 

Amid the uproar about plastic straws—including bans or pending bans in several U.S. cities—sales for paper straws are booming. But a trio of Purdue University students has a far more disruptive idea: soy straws that are 100 percent biodegradable. 

West Lafayette-based Bioanalytical Systems Inc. (Nasdaq: BASI) is reporting a fiscal second quarter net loss of $569,000, compared to net income of $66,000 during the same period last year. Despite the drop, the pharmaceutical development company saw a 60 percent increase in revenue for the quarter.

A subsidiary of New Jersey-based Covance Inc. is looking to grow its Indianapolis footprint. Covance Central Laboratory Services Inc. plans to invest nearly $17.5 million to expand its operations on the city's west side and add more than 200 jobs.  According to documents filed with the city, the drug development and global contract research company is looking to renovate 20,000-square-feet of existing space into a state-of-the-art trial testing laboratory and construct an...

The U.S. Food and Drug Administration has given another approval for a drug from Indianapolis-based Eli Lilly and Co. (NYSE: LLY). The approval for Cyramza is for the treatment of patients with hepatocellular carcinoma, the most common form of liver cancer.

Warsaw-based WishBone Medical has acquired a medical device manufacturer in Marshall County. Financial terms of the deal for Plymouth-based CSpine Inc. are not being disclosed, however a spokesperson for WishBone tells Inside INdiana Business no jobs will be affected.

Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) is reporting first quarter net income of $31.5 million, down from $72.7 million during the same period last year. Despite the drop, Chief Executive Officer Jeff Simmons says the company is seeing improved value through efficiencies and cost savings.

The Indiana Biosciences Research Institute has launched an initiative to measure public perception of the non-profit applied research center in Indianapolis.  You can participate in the anonymous and confidential survey by clicking here.

More research equipment from Greenville-based Techshot Inc. has made its way to the International Space Station. The equipment, which launched Saturday aboard an uncrewed SpaceX cargo resupply spacecraft, contains experiment modules to be used in a Massachusetts Institute of Technology tissue chip experiment.

Indianapolis-based startup LifeOmic has created an app to help people adopt the practice of intermittent fasting. Don Brown, founder and chief executive officer, says the practice isn’t only for losing weight, but can help participants reduce risk of Alzheimer's disease and Parkinson's.  Brown, who previously founded and sold Software Artistry and Interactive Intelligence, says the idea for the LIFE Fasting Tracker came from a cloud platform he used at...

Bioanalytical Systems Inc. (NASDAQ:BASI) has announced its acquisition of the business unit of Smithers Avanza Toxicology Services, a contract research organization located in Maryland. The acquired business will operate as a wholly-owned subsidiary of BASi under the name BASi Gaithersburg.

A single sheet of plastic—much like a standard piece of paper—could be the missing piece to finally win the battle against mosquito-borne diseases that cripple the health of people in developing countries. 

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) is reporting net income of $4.2 billion in the first quarter of 2019, compared to $1.2 billion during the same quarter last year. The increase was driven by the spin-off of Elanco Animal Health. The drugmaker has also cut its 2019 revenue guidance to between $22 billion and $22.5 billion, due in part to expected lower revenue for Cialis and other products that have lost patent exclusivity as well as the withdrawal of cancer drug...

A central Indiana man who broke his hip five years ago—then broke his other hip very recently—certainly faced a medical misfortune, but is also a testament to technology transforming patient care. 

Doctors in critical hospital settings make judgement calls—sometimes life or death decisions—based on information, but there’s one stat that has been notoriously difficult to obtain, says Carmel-based startup FAST BioMedical. Doctors are clamoring for a better way to determine a patient’s blood volume, an important measurement that can dictate treatment in the critical care setting. 

Life sciences experts believe Indiana’s resume of successful pharmaceutical startups sets the stage for the next generation of young companies to follow in their footsteps; among the state’s young pharma proteges are Outpost Medicine and Acacia Pharma Inc. 

Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) is reporting first quarter net income of $246 million, up from $176 during the same period last year. Despite the increase, the medical device manufacturer says it saw a more than 2 percent drop in net sales, largely due to the effect of foreign currency exchange.

Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) is adding to its portfolio with a major acquisition. The company has announced plans to acquire Kansas-based Aratana Therapeutics (Nasdaq: PETX) in a deal valued at up to $245 million. In conjunction with the acquisition, Elanco has also announced the formation of a commercial team dedicated to the veterinary specialty business. Elanco says the deal would allow it to integrate the Aratana portfolio of pet therapeutics into its...

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced plans to sell the rights in China for two of its antibiotic medicines, as well as a Chinese manufacturing facility. The deal with Eddingpharm is valued $375 million.

The Indiana Biosciences Research Institute has announced Chief Executive Officer and Chief Scientific and Innovation Officer Rainer Fischer has stepped down from both roles. The institute says Fischer, who came to Indianapolis in 2017, will remain as a senior executive for innovation and discovery. The IBRI did not provide a reason for Fischer's decision to step down. In his new role, Fischer will work to attract new partners for sponsored and contract research, as well as new...

When Bloomington-based Cook Group Inc. announced the sale of its Cook Pharmica unit to New Jersey-based Catalent Inc., company executives promised to "invest aggressively" in creating a leader in the rapidly-growing biologics sector. Eighteen months later, there is ample proof they meant it. Catalent has announced major expansion projects in recent months totaling $114 million in investment. Employment at the Monroe County facility, which stood at 270...

“Service dog” is the official name for the four-legged companion that assists a handler who has a physical disability—but many would argue best friend, companion or lifesaver are more accurate terms. However, the animals’ positive impact is only anecdotal and lacks validity in the world of science. 

Regenerative medicine has “crossed the chasm of impossible to possible,” says a nationally-renowned expert who is leading the charge in Indiana to trailblaze the “new horizon in medicine.” Indiana University School of Medicine (IUSM) Associate Vice President of Research Dr. Chandan Sen believes the new frontier will dominate the practice of medicine within a decade. 

Sweet treats and fried foods that are low in fat and calories may seem a dieter’s dream, but that’s Indianapolis-based Epogee’s mission, and it’s now backed by millions. The startup recently earned an $8.3 million investment from HG Ventures, also based in Indianapolis. 

For the second year in a row, a Manchester University faculty member has claimed a national award that recognizes early-career researchers’ discoveries in the laboratory. 

Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) has received clearance from the U.S. Food and Drug Administration for its ROSA ONE Spine System. The system is used for robotically-assisted, minimally-invasive and complex spine surgeries.

Local, state and federal leaders gathered at the Regenstrief Institute in Indianapolis this week to discuss innovations in healthcare and technology in Indiana. Indiana Startup Day included remarks from Ed Simcox, chief technology officer for the U.S. Department of Health and Human Services and also spotlighted seven Indiana healthcare startups. Brian Dixon, director of public health informatics for the Regenstrief Institute, says the goal of the event was for federal officials...

Indiana is taking part in an American Cancer Society effort looking to fuel women-led cancer research. ResearcHERS: Women Fighting Cancer aims to raise funds to support women researchers and boost programs to inspire the next generation of girls to pursue science careers. Organizers say they are looking for "ambassadors" to help meet the goal of raising $160,000 in the inaugural year of the program. Campaign co-chair Jill Geer, who is chief marketing officer at the American...

Indianapolis-based Eli Lilly and Co. (NSYE: LLY) is seeking a nearly $10 million tax abatement for a $90 million project to build and equip a facility to house insulin research and production. A City-County Council committee Monday approved the proposal, with a full council vote set for next week. The company is not committing to any new jobs as part of the project. Lilly says the project will allow it to keep up with peak and backup capacity demands for insulin products.

Indiana's life sciences initiative is boasting a strong 2018 for the sector, reporting year-over-year increases in areas including workforce, wages, exports and venture capital funding. BioCrossroads says the state's life sciences industry's economic impact is now at $79 billion. The report shows the sector supports more than 56,000 jobs in the state with an average annual wage of over $97,000. Vice President of Communications Lori LeRoy says Indiana "maintains (its) standing as...

Warsaw-based OrthoPediatrics Corp. (Nasdaq: KIDS) is reporting a full-year net loss of $12 million in 2018, compared to a loss of $8.9 million the previous year. Despite the drop, the pediatric medical device manufacturer says it hit record revenue for the year.

A West Lafayette-based startup has announced plans to scale its Indiana operations. Pinpoint Pharma, which specializes in custom compounded medication for pets, says it will invest $240,000 in lease, renovate and equip new lab space in the Tippecanoe County city and create up to 27 jobs over the next few years.  Pinpoint Pharma is one of the first five Hoosier startups to take part in the gBETA accelerator program. The Indiana Economic Development Corp. says the company...

Indianapolis-based Eli Lilly and CO. (NYSE: LLY) says one of its headache treatments is moving closer to approval. The U.S. Food and Drug Administration has granted Priority Review for a drug to be used for the preventative treatment of episodic cluster headache in adults.

In response to ongoing pressure from Congress regarding the cost of insulin, Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced plans to roll out a lower-priced version of its insulin product Humalog. The company says the authorized generic version will have a list price 50 percent lower than the current Humalog price. Lilly says it is working to make Insulin Lispro available in pharmacies "as quickly as possible." It says a single vial will list at...

A new “tiny” house on University of Southern Indiana’s campus is addressing some big issues associated with aging. Could elders live independently—and with better quality of life—in a compact house equipped with smart home technology? 

Just 18 months after entering Indiana’s life sciences landscape, Catalent says the “red hot” biologics sector is driving the company’s repeated large investments in Bloomington. 

Hoosiers in the grip of substance use disorder—especially related to opioids—have faced a shortage of professionals they can turn to for help, but a new project aims to produce more dually licensed clinical social workers specifically trained to battle Indiana’s opioid epidemic. 

Brazil-based Solinftec may be new to Hoosier soil, but it’s already harvesting accolades in the U.S.; national agriculture media outlet Successful Farming recently named it one of “8 Ag Tech Startups Worth Watching in 2019.” 

Germany-based pharmaceutical company Bayer has announced plans to close its customer logistics service center in Mishawaka. The company says the closure will take place over an 18-month transition period and will affect nearly 200 employees.

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has completed its $8 billion acquisition of Loxo Oncology Inc. (Nasdaq: LOXO) in Connecticut. Loxo Chief Executive Officer Josh Bilenker says the deal will allow the company to realize the full value of its pipeline of medicines.

West Lafayette-based Bioanalytical Systems Inc. (Nasdaq: BASI) is reporting a fiscal first quarter net loss of $85,000, compared to net income of $26,000 during the same period the previous year. Despite the drop, the company says quarterly revenue increased more than 60 percent.

The University of Indianapolis and Roche Diagnostics are partnering on an effort to fill a talent gap. The first cohort for Roche Academy has begun and the university says the goal is to solve the talent pipeline for biomedical equipment technicians. The academy provides a customized curriculum for the cohort of eight students, as well as a summer internship, that provides real-world training to prepare students for high-demand positions at Roche.

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced plans to divest its remaining interest in Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN). The pharmaceutical giant retained a more than 80 percent ownership interest in Elanco, following the company's Initial Public Offering in September.

A federal jury in Indianapolis has awarded $3 million to a Georgia woman who claimed an intravenous filter made by Bloomington-based Cook Medical was defective. Tonya Brand says she suffered medical complications after the filter deteriorated inside her body.

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) is reporting fourth quarter net income of $1.1 billion, compared to a loss of $1.7 billion the previous year, when earnings were impacted by U.S. tax reform. The company is also cuttings its revenue and profit forecast for 2019, due in part to disappointing results from a Phase 3 study of cancer drug Lartruvo. Lilly says quarterly revenue increased 4.5 percent to $6.4 billion, topping estimates. The company cites higher sales of...

Researchers at the Indiana University School of Medicine received a record amount of funding from the National Institutes of Health in 2018. The school says nearly $150 million was awarded, marking a 10 percent increase over the previous year.

Indianapolis-based Rehab Medical Inc. has announced a merger with medical device manufacturer Cork Medical, also based in Indy. Financial terms of the deal are not being disclosed, however Rehab Medical tells Inside INdiana Business it plans to add 50 jobs by the end of the year.

Indianapolis-based Eli Lilly and Co.'s (NYSE: LLY) $8 billion acquisition of Loxo Oncology Inc. (Nasdaq: LOXO) has cleared its first hurdle. Lilly says the deal has made it past the waiting period under the Hart-Scott-Rodino Antitrust Act. The acquisition was first announced in early January. Lilly says the deal will add precision medicines to its oncology portfolio.

Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) is reporting a fourth quarter net loss of $903 million, compared to net income of $1.2 billion during the same period the previous year. The medical device manufacturer says the loss included goodwill impairment and litigation charges.

A team of six Purdue University students and alumni is readjusting to life on planet Earth after spending two weeks on “Mars.” Although they didn’t travel to the real Red Planet, the crewmembers lived in isolation inside a small research station in a remote area of Utah.

Indiana is the only place in the world with a cutting-edge respiratory testing device for horses. Veterinarians and engineers at the Purdue University College of Veterinary Medicine developed the tool to bring clarity to an elusive condition. 

The Indiana Philanthropic Venture Fund (IU PhV) is on the doorstep of its one-year anniversary and, although not limited to the life sciences, it has funneled $1.6 million into the sector’s early-stage Indiana-based companies. 

Warsaw-based Nextremity Solutions, Inc. says 2018 was a critical year of validation. The orthopedic company changed its business model in 2016—moving away from its roots as a traditional startup and becoming a strategic commercialization organization. 

Indianapolis-based Beckman Coulter Life Sciences is adding to its portfolio. The company has acquired California-based liquid handling company Labcyte, though financial details were not immediately disclosed. 

A collaborative research project involving the Indiana Biosciences Research Institute has led to the discovery of a new disease. The IBRI says the monogenic disease, known as DHPS Deficiency, can lead to neurodevelopmental delay and seizures. 

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced what it calls disappointing results of a study of a new cancer drug. The pharmaceutical giant says the Phase 3 study of Lartruvo, which aims to treat patients with advanced or metastatic soft tissue sarcoma, did not meet its primary endpoints.

Bloomington-based Cook Medical has announced a sales and marketing agreement with Zelegent Inc. in California. Cook says the partnership aims to enhance treatment options for patients suffering from snoring.

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced an $8 billion deal to acquire Loxo Oncology in Connecticut. Lilly says the deal adds precision medicines to its oncology portfolio through Loxo's pipeline of medicines for patients with certain types of cancers. The Indy drugmaker says the acquisition would be the largest in its ongoing effort to strengthen its cancer treatment portfolio. Loxo's pipeline is focused on cancers that involve single gene abnormalities that can...

The Indianapolis Metropolitan Development Commission has approved tax abatement for two projects on the city's west side totaling nearly $11.5 million. According to documents filed with the city, the developments would create and retain nearly 60 jobs. Indianapolis-based Sentry Ventures LLC is planning to invest nearly $9 million to build and equip a 30,000-square-foot addition to its existing facility and Japan-based Ryoei USA Inc. is looking to invest $2.5 million to build a...

The shareholders of West Lafayette-based Endocyte Inc. (Nasdaq: ECYT) have approved the previously-announced $2.1 billion acquisition agreement with Switzerland-based pharmaceutical company Novartis AG. The company says the deal is expected to close Friday.

West Lafayette-based Bioanalytical Systems Inc. (Nasdaq: BASI) is reporting a fiscal full-year net loss of $194,000, compared to net income of $884,000 the previous year. The company says the results are due in part to one-time costs associated with its July acquisition of Missouri-based Seventh Wave Laboratories LLC.

There’s a lot of conjecture about cancer in the world of firefighting, but a crescendo of anecdotal—and scientific—evidence is driving two Indiana researchers to search for answers. 

Romaine has returned to store shelves after a recent E. coli outbreak stopped salads at both grocers and restaurants. Science is partly to blame; the U.S. Food and Drug Administration (FDA) recalled all romaine as a broad safety measure, because detecting pathogens such as E. coli takes time in the lab—up to three days in some cases. 

‘How do we feed 9 billion people by 2050?’ is a common rallying cry—and foreboding challenge—within the agricultural community. But a young company from the Boston area—now opening its next operation at Purdue Research Park in West Lafayette—says the right question to ask is, ‘How do we feed the world without destroying the planet?’ 

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced 2019 financial guidance, with projected revenue and adjusted profit above analyst expectations. The company says the growth is driven by demand for newer medicines including Trulicity, for diabetes, and psoriasis drug Taltz. The company is projecting 2019 revenue between $25.3 billion and $25.8 billion, and earnings per share between $5.52 and $5.62. Chief Executive Officer David Ricks says, while he's happy with...

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced an agreement with Massachusetts-based Hydra Biosciences. The company says it has acquired all assets related to a pre-clinical program from Hydra, though financial terms of the deal are not being disclosed.

The incoming interim president and chief executive officer of BioCrossroads says the transition in leadership will be a smooth one. The state's life science initiative announced Wednesday longtime CEO David Johnson is leaving to continue his role as CEO of the Central Indiana Corporate Partnership on a full-time basis. Norah Doherty will assume the interim position at the beginning of the year and says BioCrossroads continues to look to the future.

16 Tech developers have officially broken ground on the innovation district's first building, marking the beginning of an ambitious 10-year project. The $30 million Advanced Research and Innovation building is fully-leased and will anchor the 60-acre development. The facility, which will house the Indiana Biosciences Research Institute, Central Indiana Corporate Partnership and Indiana University School of Medicine researchers, is set to be complete in mid-2020.

The chief executive officer of the state's life sciences initiative is stepping down. BioCrossroads says David Johnson, who has led the organization for 14 years, is leaving at the end of the year to serve as president and CEO of the Central Indiana Corporate Partnership on a full-time basis. The CICP is the parent organization of Indiana's six talent and industry sector initiatives, including BioCrossroads. Johnson was elected president and CEO of the CICP in 2012 and has since led...

Warsaw-based OrthoPediatrics Corp. (Nasdaq: KIDS) has begun a public stock offering. The pediatric medical device manufacturer is looking to raise up to nearly $47 million as a result of the offering, which is expected to close Tuesday.

The University of Notre Dame has signed a strategic alliance agreement with the Indiana Biosciences Research Institute in Indianapolis. The IBRI says the agreement will enable both parties to "work together on research covering significant health issues in Indiana and around the world."

BioCrossroads' educational efforts have received a boost from a grant from the Richard Fairbanks Foundation. The organization received a $1.48 million grant to advance opportunities in Indiana's life sciences and healthcare sectors.

New Jersey-based Catalent Inc. (NYSE: CTLT) has announced plans to grow its Bloomington operations. The company says it will invest nearly $14 million to expand its biologics packaging capacity at its Monroe County manufacturing facility and create 36 jobs. Catalent entered the Bloomington market in 2017 with its $950 million acquisition of Cook Pharmica. The company says it will construct a 15,000-square-foot addition that will include...

A jury in Marshall County has awarded what is being called one of the largest verdicts in Indiana history to an Indianapolis spine surgeon and inventor. Rick Sasso would receive more than $112 million in royalties and interest which he claimed he was owed by Minnesota-based medical device company Medtronic PLC (NYSE: MDT).

The Apple Watch is no longer just a fitness tracker—a new app developed by Warsaw-based Zimmer Biomet Holdings, Inc. is like “a live-in physical therapist,” says one Hoosier orthopedic surgeon.