Regenstrief Scientist Helping Lead $21M Study

Posted: Updated:
(Image courtesy of IUPUI) (Image courtesy of IUPUI)
INDIANAPOLIS AND WASHINGTON D.C. -

A research scientist with the Regenstrief Institute in Indianapolis and the U.S Department of Veterans Affairs has been chosen to co-lead a national study to find a way to manage chronic lower back pain. The Department of Veterans Affairs is funding the $21 million, 20-site trial. Dr. Matthew Bair is leading the study with Dr. David Clark, who works from the VA Palo Alto Health Care System and Stanford University. 

The National Institute of Neurological Disorders and Stroke reports 80 percent of adults experience lower back pain at some point in their lives, which makes it the most disabling chronic condition in the world. Researchers say about 20 percent of those affected by acute low back pain develop pain that lasts 12 weeks or more, which is classified as chronic low back pain, which is difficult to treat. 

“We have an amazing opportunity to hopefully make a very large impact with this trial,” Dr. Bair said. “We believe this study could have greater implications for the treatment of chronic lower back pain in the general population.”

The study is called the Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response (SCEPTER) trial, which is designed in two steps, to first randomly divide participants among three different treatments. Some will be assigned to a web-based program of self management, while others will be involved with physical therapist-led exercise programs and face-to-face appointments. The third group will receive the usual care for lower back pain, which includes ice/heat, rest and pain medication. Step two of the trial will compare yoga, chiropractic care and cognitive behavioral therapy where participants will be given the option to undergo a random therapy again, or allowed to opt out to be randomized in the other two groups. 

“This study is unique because it incorporates patient preferences,” said Dr. Bair. “We feel that patient preferences do predict treatment response, so patients are more likely to benefit from a treatment they prefer than one they don’t.” 

The six-year trial will include over 2,500 veterans at 20 sites. Funding was provided by the VA Cooperative Studies Program. 

  • Perspectives

    • What’s Your Biggest Waste of Money?

      Americans are in the age of reducing waste. There’s a big push to purchase sustainable products, reduce our usage of plastics, and recycle. But has this trend carried over to our personal finances?  Not really.  In a study by The Ascent, the financial expertise arm of The Motley Fool, more than 60 percent of respondents felt they have wasteful financial tendencies. Why is that?

    More

Subscribe

Name:
Company Name:
Email:
Confirm Email:
HTML
INside Edge
Morning Briefing
BigWigs & New Gigs
Life Sciences Indiana
Indiana Connections
INPower
Subscribe
Unsubscribe

Events



  • Most Popular Stories

    • POET ethanol co. announced in Aug 2019 it was closing the plant in Cloverdale. (photo courtesy: POET)

      Cloverdale Ethanol Plant Closes

      South Dakota-based POET LLC, the nation’s largest biofuels producer, is moving forward with a plan to shut down its biorefining plant in Cloverdale, leaving 50 Hoosiers without jobs effective Friday. The company tells Inside INdiana Business that it is not making any changes to the plans announced two months ago. 

    • (IIB Photo/Joe Ulery)

      Neighborhood Concerned About Old GM Site, Too

      As the city of Indianapolis and Ambrose Property Group squabble about the future of the old GM Stamping plant site in downtown Indy, a fight that could end up in court, residents who live near the property are weighing in with their concerns. Jay Napoleon, president of The Valley Neighborhood Association, says it’s important the mixed-use vision for the property remain intact. Napoleon and Ambrose Property Group Vice President Mali Simone Jeffers talked about the future of...

    • (Image of downtown Shelbyville courtesy of Mainstreet Shelbyville Inc.)

      Shelbyville Unveils Major Downtown Redevelopment

      The city of Shelbyville is announcing what it calls a major downtown redevelopment project to boost overall quality of life. The project plans feature green spaces, increased parking, market-rate housing, and infrastructure for public entertainment and community events. 

    • What’s Your Biggest Waste of Money?

      Americans are in the age of reducing waste. There’s a big push to purchase sustainable products, reduce our usage of plastics, and recycle. But has this trend carried over to our personal finances?  Not really.  In a study by The Ascent, the financial expertise arm of The Motley Fool, more than 60 percent of respondents felt they have wasteful financial tendencies. Why is that?

    • The IU School of Informatics, Computing and Engineering will now be named for Fred Luddy for his $60M gift. (photo courtesy James Brosher/IU)

      $60M Gift to Fund AI Center

      An Indiana University alumnus who founded the information technology firm, ServiceNow, has given his alma mater $60 million to establish an artificial intelligence center. The university says the gift from cloud-computing pioneer Fred Luddy is the second largest in the history of the IU.