Lilly, AstraZeneca End Trials Early

Posted: Updated:
(Image courtesy of Eli Lilly and Co.) (Image courtesy of Eli Lilly and Co.)
INDIANAPOLIS -

A series of trials for a potential Alzheimer's disease treatment being tested by Indianapolis-based Eli Lilly and Co. (NYSE: LLY) and AstraZeneca has been called off. The companies have accepted the recommendation of an independent data monitoring committee to discontinue late-stage trials of lanabecestat. The committee concluded trials involving participants in early stages of the disease and mild cases of the disease, as well as a related extension trial, would all be unlikely to meet primary endpoints.

Lilly Research Labs President Daniel Skovronsky says "the complexity of Alzheimer's disease poses one of the most difficult medical challenges of our time, and we are deeply disappointed for the millions suffering from this devastating disease. We are grateful for the contributions of the study participants and their families and encourage them to consider other Alzheimer's disease clinical trials. Lilly remains dedicated to Alzheimer's disease research as we have been for the last three decades. We won't give up on finding a solution for Alzheimer's patients."

In a press release, the companies point out the studies were not stopped based on safety concerns. Lilly says the discontinuation decision is not expected to create "significant costs."

AstraZeneca IMED Biotech Unit Executive Vice President Menelas Pangalos says "we are saddened by this outcome as our researchers are working tirelessly to find a solution for the many people who are impacted by this devastating disease. We are committed to ensuring our findings can be used to inform further research in the Alzheimer's community, given the importance of finding a treatment for this disease."

You can connect to more about the decision by clicking here.

  • Perspectives

    • Mitigating Your Company’s Cybersecurity Risk

      Frequently, I encounter people who think that a software developer understands all languages and can “fix” anything tech related. While that may be true for a few, areas of expertise within tech evolve as rapidly as the technology itself. For instance, there was a time (not long ago) when operating in the cloud was revolutionary. Today, it is considered best practices for some or all of an organization to function within a cloud. Managed information technology began with...

    More

Subscribe

Name:
Company Name:
Email:
Confirm Email:
HTML
INside Edge
Morning Briefing
BigWigs & New Gigs
Life Sciences Indiana
Indiana Connections
INPower
Subscribe
Unsubscribe

Events



  • Most Popular Stories

    • (photo courtesy Dax Norton)

      Whitestown Tops Indiana's Fastest-Growing Communities

      The Indiana Business Research Center at the Indiana University Kelley School of Business says Whitestown in Boone County is Indiana's fastest-growing community for the eighth consecutive year. The center says the town's population nearly tripled, from 3,132 in 2010 to 8,627 last year. Westfield in Hamilton County is not far behind. Its population grew 5.2 percent in 2018, according to information reported by the U.S. Census Bureau. Other communities on the list include...

    • (Image courtesy of the Indiana Economic Development Corp.)

      Indy-to-Paris Flight Celebrates One Year

      One year after the first nonstop flight from Indianapolis International Airport to Paris, Airport Authority Executive Director Mario Rodriguez says the flight is "fully meeting our expectations." He says, on average, more than 1,000 passengers per week fly between Indianapolis and Paris. Delta Air Lines Flight 500 marked IND's first year-round, nonstop transatlantic air service to Europe. The airline increases the route's frequency throughout the spring, summer and fall...

    • (photo courtesy of Farmer's Fridge)

      Farmer's Fridge Expands to Indianapolis

      A Chicago-based company is looking to make fresh, healthy food as convenient in Indianapolis as a candy bar. Farmer’s Fridge has expanded to more than a dozen locations in the Indy market with its "smart fridges" the size of vending machines, which feature a variety of freshly-made products such as salads, bowls and snacks. Rachel Rischall, director of communications for Farmer's Fridge, says the food is made fresh every day and shipped to nearly 300 fridges in...

    • The Waterside project aims to transform 100-acres of the former GM Stamping Plant site. (photo courtesy of Ambrose Property Group)

      Ambrose, Glick Partner on Waterside

      Indianapolis-based Ambrose Property Group has announced a key partnership for the redevelopment of the former GM Stamping Plant in downtown Indianapolis. The commercial real estate firm is teaming up with the Gene B. Glick Co. to build and manage apartments as part of the $1.4 billion mixed-use redevelopment project. Ambrose says the partnership is also part of plans to catalyze "philanthropic and community-centric strategies to strengthen Indianapolis." The firm also...

    • Pearl will take the position on May 22

      Bloomington Launches Online Economic Development Tool

      The city of Bloomington has officially launched its new online development tool. The platform will streamline public data for current and prospective business owners and entrepreneurs.