Lilly Reports 'Unfortunate' Study Results

Posted: Updated:
INDIANAPOLIS -

Indianapolis-based Eli Lilly and Co. (NYSE: LLY) says results of a Phase 3 study for the drug Verzenio did not meet its primary endpoint in the treatment of advanced lung cancer. The drug, also known as abemaciclib, has already received FDA approval as a treatment for breast cancer.

Lilly says the JUNIPER study evaluating Verzenio was designed to evaluate the efficacy and safety of the drug in patients with state IV non-small lung cancer who have received chemotherapy. Levi Garraway, senior vice president of global development and medical affairs for Lilly Oncology calls the outcome of the study "unfortunate."

"We remain encouraged by the antitumor activity observed with abemaciclib in this form of lung cancer where few clinical advances have been achieved," said Garraway. "As we analyze secondary endpoints and explore specific patient subgroups in order to better evaluate the prospects for abemaciclib in NSCLC, we will continue to work with the oncology community to inform potential future treatment avenues for patients with KRAS-mutated advanced lung cancer. Moreover, we have several studies ongoing of rational combinations that include abemaciclib in non-small cell lung cancer and other malignancies. We look forward to seeing the results of these studies."

Lilly says it will submit the data from the duty at a medical meeting in 2018. You can read more about the results by clicking here.

  • Perspectives

    • Indiana's Workforce is Mission: Critical

      Indiana is ranked the #10 Best Place to Do Business, #4 for Quality of Life, #1 for Regulatory Environment and #2 for Software Job Growth. Indianapolis is ranked #3 for Tech Jobs for Women. We have four of the top 25 Best Places to live in America, with my hometown of Fishers topping the list. Yet, in spite of these amazing rankings, we have some serious challenges to overcome within our economic development ecosystem, not the least of which is skilling up a workforce to meet demand.

    More

Subscribe

Name:
Company Name:
Email:
Confirm Email:
HTML
INside Edge
Morning Briefing
BigWigs & New Gigs
Life Sciences Indiana
Indiana Connections
INPower
Subscribe
Unsubscribe

Events



  • Most Popular Stories

    • 'Best Places' in Indiana Reaches Record

      The Indiana Chamber of Commerce has released the 2018 list of Best Places to Work in Indiana. A record 125 companies are being honored this year and more than 50 are first-timers or returning after a year or more off the list. Employers in over two dozen communities are represented and the chamber will unveil the rankings of the Best Places honorees during a May 3 awards dinner at the Indiana Convention Center in downtown Indianapolis.

    • Cook Details Major Realignment

      The president of Bloomington-based Cook Medical says changes to the company's organizational structure will drive more rapid technology innovation and continued growth. Cook is restructuring from 10 business units to two divisions, a move that will impact sales, marketing, research and development, and customer service teams. It will also establishing new distribution channel management and medical education teams. In an interview with Inside INdiana Business, Pete Yonkman said...

    • Indiana's Workforce is Mission: Critical

      Indiana is ranked the #10 Best Place to Do Business, #4 for Quality of Life, #1 for Regulatory Environment and #2 for Software Job Growth. Indianapolis is ranked #3 for Tech Jobs for Women. We have four of the top 25 Best Places to live in America, with my hometown of Fishers topping the list. Yet, in spite of these amazing rankings, we have some serious challenges to overcome within our economic development ecosystem, not the least of which is skilling up a workforce to meet demand.

    • Cummins to Design Combat Engines That Elude the Enemy

      The monstrous, larger-than-life military tanks of tomorrow could be powered by Hoosier ingenuity. A recent $47 million defense contract delivers marching orders for Columbus-based Cummins Inc.: develop the next-generation engine to power U.S. combat vehicles, and it must be stronger, but smaller, and elusive to enemies’ efforts to spot it. 

    • Hendrickson Leaves State Personnel Department

      Indiana State Personnel Department Director Brandye Hendrickson has been appointed deputy administrator of the Federal Highway Administration. Governor Eric Holcomb appointed Hendrickson INSPD director in January. Prior to that, she worked at the Indiana Department of Transportation in various roles since 2006—including INDOT commissioner from 2015 to 2017.