Grant to Help Alzheimer's Study Begin

Posted: Updated:
Liana Apostolova will lead the study. (photo courtesy Indiana University) Liana Apostolova will lead the study. (photo courtesy Indiana University)
INDIANAPOLIS -

The National Institute on Aging has awarded the Indiana University School of Medicine a $7.6 million grant to study early-onset Alzheimer's disease. IU says the grant will support what will ultimately be a $45 million research program.

The grant will help establish an infrastructure and begin recruitment for the program, which will be led by Liana Apostolova, professor of Alzheimer's disease research at the IU School of Medicine. The university says the study aims to "better understand how people develop this rare variant of the disease.

Apostolova says about 5 percent of Alzheimer's patients develop symptoms before age 65 and fewer than 10 percent of those patients carry known mutations for the disease. She says early-onset patients are typically excluded from clinical research and therapeutic trials because of their age or lack of memory loss.

"The data collected as part of this study will provide a definitive comparison of the clinical, psychometric, imaging, fluid biomarker and genetic similarities and differences between early-onset and late-onset Alzheimer’s disease," said Apostolova.

The study, known as Longitudinal Early-onset AD Study, or LEADS, will create a network throughout the country in which a large cohort of early-onset Alzheimer's patients will be enrolled. The study also involves researchers from the University of California - San Francisco, Harvard University and the Alzheimer's Association.

  • Perspectives

    • An Antidote For First-Time Homebuyer Jitters

      If you're a Millennial like I am, chances are you're in the market to purchase your first home. It's exciting!  But since it's most likely the largest purchase you've ever made, it can quickly turn into a nerve-racking endeavor. Having just completed a transaction, I found that following these guidelines can ensure a smooth process. Every homebuyer's experience will be different because of a number of variables such as what state you live in and the condition of the housing mark...
    More

Subscribe

Name:
Company Name:
Email:
Confirm Email:
HTML
INside Edge
Morning Briefing
BigWigs & New Gigs
Life Sciences Indiana
Indiana Connections
INPower
Subscribe
Unsubscribe

Events



  • Most Popular Stories

    • (Image of Gene Renuart courtesy of the Indiana Innovation Institute.)

      Agreement Paves Way For More Trusted Microelectronics Collaboration

      A new four-way partnership aims to boost the state's national position in the field of trusted microelectronics. The Indiana Innovation Institute, the Crane Naval Surface Warfare Center, Indiana University and Purdue University have inked a cooperative research and development agreement that officials say will drive research, talent and economic development. The collaboration will work to develop microelectronics that are...

    • The Finish Line Acquisition Complete

      The nearly $560 million acquisition of Indianapolis-based The Finish Line Inc. is complete. The deal by JD Sports Fashion plc, a retailer headquartered in the United Kingdom, was announced in March. Finish Line shareholders last week approved the transaction. The Finish Line is now a wholly-owned subsidiary of JD Sports. Finish Line Chief Executive Officer Sam Sato will remain with the surviving corporation and will maintain a seat with the board of directors.

    • (Image courtesy of IU Health West.)

      IU Health West President Updates $80M Expansion

      As executives continue to receive feedback about an $80 million expansion of Indiana University Health West Hospital in Avon, newly-appointed President Art Vasquez says the project is focused on the future. Plans call for four dozen additional beds, a new operating room and additional laboratory and support service space. Vasquez tells Inside INdiana Business capacity issues at the 14-year-old Hendricks County facility have led to hundreds of patients a year being transported elsewhere.

    • Delta Begins Nonstop to Seattle

      Delta Air Lines now offers a nonstop flight from Indianapolis International to Seattle-Tacoma International Airport. The first flight leaving Monday night will be a milestone for the Indy airport, since it will now connect to all Delta hubs in the U.S. 

    • (photo courtesy of our partners at the Daily Journal)

      Bargersville Company to Partially Relocate

      A nearly 80-year-old company in Johnson County is looking to expand. Our partners at the Daily Journal report Bargersville-based Roy Umbarger and Sons is planning to invest $13 million to relocate its feed division to a site near Franklin.