NIH Awards $4.4M Grant to IU School of Medicine

Posted: Updated:
INDIANAPOLIS -

The National Institutes of Health has awarded two five-year grants totaling $4.4 million to the Indiana University School of Medicine. The funding will support research to identify new treatments for a family of fatal genetic diseases.

The university says researchers are looking for ways to combat glycogen storage diseases, such as Lafora and Pompe diseases, which can causes fatal illnesses.

"These diseases are rare but nonetheless devastating not only for the patients but also their family and friends," said Peter Roach, distinguished professor of biochemistry and molecular biology. "Our group has met with Lafora families at workshops organized by their foundation, Chelsea's Hope, and it is humbling to hear of their ordeals and their faith that we can find a cure or, at least, a treatment. We sincerely hope that this new funding can help us reach that goal by developing a novel therapy."

The team at the IU School of Medicine has found ways to alleviate the symptoms of these diseases in genetically modified mice by decreasing glycogen accumulation. Roach says his team is focusing developing small-molecule drugs to perform this task.

The NIH grant adds to existing funding for the research, including a $2.2 million grant from the National Institute of Diabetes, Digestive and Kidney Diseases and a $9.1 million Program Project Grant from the National Institute of Neurological Disorders and Stroke.

  • Perspectives

    • Creating the Work Spaces that Draw Talent to Indianapolis

      The future economy will be driven by data, powered by robotics and heavily invested in the building blocks of nature – biotech and genetic engineering. That’s true of the economy nationwide, and it’s especially true here in Indianapolis, where dominant pharmaceutical and biotech companies are putting us at the cutting edge of the science-based economy. It all sounds larger than life. But the facilities that will house these industries will always be...

    More

Events



  • Most Popular Stories

    • Allison and Stanley Chen provided the lead gift for the campaign. (Provided Photo/ISI)

      International School Launches Capital Campaign

      The International School of Indiana has publicly launched a capital campaign to establish a unified campus in Indianapolis. As part of the ONE ISI campaign, the school is looking to raise $6.5 million to build a new school building for pre-elementary and elementary students at the site of its middle and high schools. The public launch follows a 10-month silent phase of the campaign, during which ISI raised $5 million from more than two dozen donors. Currently, ISI's operations are...

    • Money magazine judges Fishers as 3rd best place to live in the U.S.

      Fishers Makes Top 10 List of 'Best Places to Live'

      Three communities in Indiana made the top 100 list of best places to live in the country, but only one made the top 10. Fishers was judged by Money magazine as the third best place to live in the United States, behind Clarksville, Tennessee and Round Rock, Texas.

    • Lt. Governor Suzanne Crouch will be on hand for the announcement.

      Jobs Announcement Set for Indy

      City and state officials will Wednesday make a jobs announcement in downtown Indianapolis. Few details are available, however the Indiana Economic Development Corp. says leaders from an Indianapolis-based startup will be involved.

    • (photo courtesy of Dickinson Fleet Services)

      Dickinson Fleet Services Expands; Grows Talent Pool

      Indianapolis-based Dickinson Fleet Services is expanding its truck maintenance reach with the purchase of A1 Diesel Service of Hendersonville, Tennessee. Dickinson says this is its ninth acquisition since 2017 and the third in 2019. 

    • Photo courtesy of Bristol Parks

      Startup Plans to Add 250 Jobs By 2021

      A metal forming startup is seeking to use a facility in Bristol that has been empty since 2017 for a major manufacturing operation. The Elkhart Truth reports Brinco will invest $52 million in the project and add 250 jobs.