• IBRI is one of many life science organizations to collaborate on the new app

    Life Science Companies Launch Information Source

    Seven life science organizations in Indiana are collaborating on a one-stop shop for information, called INscience. BioCrossroads, Cook Regentec, Corteva Agriscience, Eli Lilly and Co., Indiana Biosciences Research Institute, Indiana Clinical and Translational Sciences Insititute and Roche Diagnostics have teamed to educate and engage Indiana's $78 billion life sciences economy. 

  • The startup is part of the Purdue Foundry.

    Purdue Foundry to Showcase First Accelerator Cohort

    The Purdue Foundry is set to unveil its first cohort for the Double Down Experiment, which includes nine high growth businesses the organization says are ready to reach the next level. The Purdue Foundry is co-hosting The Big Show, to showcase the innovators and business builders selected for the program.

  • (photo courtesy of Indiana Economic Development Corp.)

    BraunAbility Opens New Carmel Headquarters

    An Indiana company that specializes in wheelchair lifts and van conversions so they’re wheelchair-accessible has announced plans to increase the number of workers with disabilities. BraunAbility made that announcement as it opened its new global headquarters in Carmel. 

  • Alan Palkowitz (at podium) will lead the new center. (Inside INdiana Business Photo/Mary-Rachel Redman)

    Grant Creates IU Alzheimer's Center

    The National Institutes of Health has awarded a $36 million grant to the IU School of Medicine to launch a drug discovery center focused on accelerating the development of treatments for Alzheimer's disease. The center is part of a strategic partnership with the Purdue Institute for Drug Discovery, and IU says the partnership is one of only two multi-institution teams in the country selected for a new federal program designed to grow the drug development pipeline for the disease.

  • Vanessa Barth (Inside INdiana Business Photo/Mary-Rachel Redman)

    New BioCrossroads Challenge Combines Life Sciences, Data

    Indiana's life sciences initiative is launching a new competition designed to help solve two health issues facing Hoosiers: diabetes and opioid abuse. BioCrossroads says the DataX BioInnovation Challenge was created to "intersect life sciences and data research," giving innovators the opportunity to use data sets to identify and investigate hypotheses to improve the health issues. The winning team or teams could receive up to $50,000 cash. In an interview with...

  • 'Grandfather of EMR' Named Life Sciences Champion

    Today at the Indiana Life Sciences Summit, BioCrossroads’ Board of Directors named Dr. Clem J. McDonald recipient of the 2019 August M. Watanabe Life Sciences Champion of the Year Award. The prestigious honor named in tribute to BioCrossroads’ late Chairman August Watanabe, was given to Dr. McDonald for his unprecedented impact on health IT and digital health in Indiana and abroad. 

  • The MATRIXX Stand Alone Cervical device recently earned FDA clearance.

    Latest 3D-Printed Device Boosts Nexxt Spine

    An orthopedic medical device company in central Indiana that has been quietly growing for the last two decades admits “we’re a big secret, but we don’t mean to be.” Noblesville-based Nexxt Spine has launched its latest product and is aiming to “spread the word” about its growing device portfolio. 

  • IU researchers say a growing number of pregnant women are being prescribed opioids (image courtesy public domain pics by Pixabay).

    Pain During Pregnancy: IU Examines Impact of Prescribed Opioids

    Studies have already uncovered the dangerous impact on babies when mothers have opioid abuse disorder, and other research has examined the use of opioids to treat opioid abuse disorder. However, Indiana University scientists are now addressing an unanswered question: what about expectant mothers who are prescribed the medications to treat pain? 

  • Karyosoft says its technology unites microbiome data in one easy-to-use system.

    Carmel Entrepreneur Invents ‘Google of Microbes’ Software

    There is much excitement surrounding microbes in life sciences research—and for good reason. Dr. Rajesh Perianayagam says scientists have discovered 17 microbiome-related cures and therapies for an equal number of diseases. But this flurry of excitement—and the recent proliferation of genetic sequencing technology—is drowning scientists in data. 

  • Life Sciences Company Spins Out, Raises $5M

    The first company to spin out of Indianapolis-based Cook Regentec has secured $5 million in growth capital. Sexton Biotechnologies, also based in Indy, says it will use the funding to expand and scale the commercialization of its portfolio.

  • (AgriNovus CEO Beth Bechdol (seated right) announces changes to Forbes AgTech Summit)

    Showcasing Indiana at Forbes AgTech Summit

    National and global leaders in the worlds of agriculture, technology, and science have closed out the 2019 Forbes Ag Tech Summit in Indianapolis, now in its second year in the state. The event gathered industry leaders and entrepreneurs who are looking for answers to the challenges of growing and producing food. The two-day summit, hosted by AgriNovus Indiana, addressed food animal health, protein and crops.

  • Zimmer Biomet is headquartered in Warsaw.

    Zimmer Biomet Device Receives FDA Clearance

    The U.S. Food and Drug Administration has awarded clearance to Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) for a meniscal repair device. The medical device manufacturer says the device, known as JuggerStitch, will be available in the U.S. market.

  • Indy Biotech Firm Wants to Change Rx Delivery

    Indianapolis-based Toralgen Inc. says it has raised nearly $2 million in seed funding for what the company calls its transformative drug delivery tool. The biotechnology firm is attempting to commercialize a nanopill system, a microscopic-sized dose of medication, for diabetes control and other diseases.

  • IU Ventures Invests $500K in Medical Biotech Firm

    Carmel-based MBX Biosciences Inc. has received a $500,000 investment from the Indiana University Philanthropic Venture Fund. The medical biotech firm, whose founders include high-profile inventor Dr. Richard DiMarchi, has developed therapeutics to treat endocrine diseases.

  • (Provided Photo/Zimmer Biomet Holdings)

    Law Firm Investigating Zimmer Biomet

    A California-based shareholder rights litigation firm is investigating Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH). The Schall Law Firm says its investigation, being conducted on behalf of Zimmer Biomet investors, is related to claims of failing to disclose information pertinent to investors.

  • (photo courtesy IUPUI)

    IUPUI Researcher to Study Quality of Life in Cancer Patients

    An IUPUI psychologist has been awarded a nearly $2 million grant from the National Cancer Institute for her research to help cancer patients, in advanced stages of the disease, to still find quality of life while accepting the eventual outcome. The university says Professor Catherine Mosher is investigating a novel acceptance-based approach of facing the disease, while fighting the fatigue and other systems seen in late-stage cancer patients.

  • The app also connects Hoosiers to some 1,600 clinical trials throughout the state.

    Indiana-Made App Targets Hoosier Health, Research

    An Indianapolis-based tech company and a research powerhouse are combining forces to put health at Hoosiers’ fingertips with a new mobile app. While the market may seem saturated with health apps, the creators of LIFE Extend—tech startup LifeOmic and the Indiana Clinical and Translational Sciences Institute (CTSI)—believe the new tool is one-of-a-kind. 

  • Micropulse says it grew 18 percent last year and expects to grow about 15 percent in 2019.

    Micropulse on the Grow Again

    Micropulse Chief Executive Officer Brian Emerick says any other manufacturer can make the same orthopedic devices as his company; instead, the blueprint for success at the Columbia City-based contract manufacturer centers on culture. Micropulse, which started 31 years ago in his garage, has produced steady, incremental growth “organically, by word of mouth and brand,” and Emerick believes the strategy is delivering again with a $6.8 million expansion. 

  • Newton says IU’s world-class facility in fruit fly genetics makes the university, “hands-down,” the best place to do her work.

    $1.8M Grant Boosts Biologist’s Disease-Fighting Research

    Focusing on “the deadliest animal on Earth,” an Indiana University biologist is trying to cripple a dangerous killer: the mosquito. While mostly just a nuisance swatted away in the U.S., IU Biology Associate Professor Dr. Irene Newton says, “you can think of the mosquito as the apex predator on the planet, because the diseases it carries kill so many people.” 

  • Seleem says repurposing an existing drug is much less costly than developing a new drug.

    PU Prof Targets Hospital-Acquired Infection

    Among hospital-acquired infections, MRSA gets most of the attention, says a Purdue University researcher; this leaves the second most common hospital-acquired infection lurking in the shadows. Vancomycin-resistant enterococci (VRE), similar to MRSA, is characterized by its antibiotic resistance, making it especially dangerous and difficult to treat. 

  • Elanco is headquartered in Greenfield.

    Elanco to Acquire Bayer AG Animal Health Business

    Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) has entered into an agreement with Bayer AG (ETR: BAYN) to acquire its animal health business in a deal valued at $7.6 billion. If approved, it would double Elanco’s Companion Animal business and create the second-largest animal health company by revenue. “Joining Elanco and Bayer Animal Health strengthens and accelerates our IPP strategy, transforms our portfolio with the addition of well-known pet brands, brings...

  • (rendering courtesy NEXXT Spine)

    Noblesville Company Receives FDA Clearance

    Noblesville-based Nexxt Spine LLC has received clearance from the U.S. Food and Drug Administration for its NEXXT MATRIXX Stand Alone Cervical System. The system is a "stand-alone anterior cervical interbody fusion system" intended to be used for treatment of degenerative disc disease.  

  • (Image courtesy of Elanco)

    Report: Elanco, Bayer Deal Could Come Soon

    A new report from Bloomberg says an agreement between Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) and Germany-based Bayer AG could be announced as soon as next week. The news service reported Wednesday the two companies are looking to announce a deal involving Bayer's animal health unit around the time of Elanco's earnings release, which will take place Tuesday. Bloomberg, citing sources who asked to not be identified due to the private nature of the discussions...

  • Columbia City-based Micropulse Inc announces expansion

    Medical Device Maker Growing in Whitley County

    A Whitley County-based medical device manufacturer is expanding its northeast Indiana operation and adding about two dozen jobs. Columbia City-based Micropulse Inc., says it is investing $6.8 million to expand, equip and better utilize its 160,000-square-foot facility. 

  • Columbia City-based Micropulse Inc announces expansion

    Medical Device Maker Growing in Whitley County

    A medical device manufacturer in Whitley County is growing its operations. Micropulse Inc. has announced plans to invest nearly $7 million to expand its Columbia City facility and create up to 25 jobs by the end of 2020. The Indiana Economic Development Corp. says the company will add 15,000 square feet to its 160,000-square-foot facility, while also renovating 3,000 square feet of existing space to make it "better suited for growth." The company says the project will allow...
  • Rogo plans to expand its fleet to four robots by the fall.

    Soil Sampling Robot Lands $200K, Grows Fleet

    Farmers spend big bucks on fertilizer; a West Lafayette-based startup says it’s typically the third highest per-acre expense. Farmers rely on soil sampling—typically done by hand—to determine how much fertilizer to apply to their fields and where to spray it. 

  • Exelead is currently manufacturing 22 commercial products, up from four in 2016.

    Demand for Liposomes Launches $25M Exelead Expansion

    Indianapolis-based Exelead specializes in small, but it means big business. The contract development and manufacturing company makes the final formulations for drugs that treat rare and small populations; “large-scale pharmaceutical companies wouldn’t touch some of the products we manufacture, because of scale,” says Chief Executive Officer John Rigg. 

  • Ziaie believes the elderly—especially those with dementia, Alzheimer’s disease or living in nursing homes—could benefit most from the diaper sensor.

    UTI Sensor for Diapers Nears Commercialization

    Urinary tract infections (UTIs) are one of the most common infections in elderly and children, yet these two groups may also be unable to alert caregivers when they have symptoms. A Purdue University researcher has developed a tool to safeguard against children and elderly suffering from the elusive infections. 

  • The hops growing system will be shipped to customers in a single box for about $600.

    Fort Wayne Startup Creates ‘Hopportunity’ for Microbreweries

    An innovation is brewing in Fort Wayne for craft beer businesses or even hobbyists making their ale at home. Two companies are combining their expertise to create a “kit” to grow hops at home or on small acreage. 

  • Lilly Swings to Quarterly Profit

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) is reporting second quarter net income of $1.3 billion, compared to a net loss of $260 million during the same period last year. The company says the results were driven, in part, by several U.S. Food and Drug Administration approvals.

  • Elanco is headquartered in Greenfield.

    Elanco Finishes Deal on Pet Therapeutics Purchase

    Greenfield-based Elanco Animal Health Inc.(NYSE: ELAN) completed its purchase Thursday of Aratana Therapeutics (Nasdaq: PETX), a pet therapeutics company located near Kansas City. As Inside INdiana Business first reported Tuesday Aratana shareholders voted overwhelmingly in favor of the $245 million deal. 

  • (Image courtesy of Elanco)

    Elanco Acquisition Moves Forward

    Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) is one step closer to adding to its portfolio. Shareholders of Aratana Therapeutics Inc. (Nasdaq: PETX), voted overwhelmingly in favor of proposed $245 million purchase by Elanco.

  • Elanco is headquartered in Greenfield.

    Report: Elanco, Bayer in Merger Talks

    Just four months after finalizing its split with Eli Lilly and Co. (NYSE: LLY), Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) is reportedly in talks with Germany-based Bayer over a possible merger with its animal health division. According to Reuters news service, the two companies are working with banks to ensure any merger would receive regulatory approval. Elanco was part of Lilly for six decades until it was spun off into an independent public company last fall.

  • Eli Lilly Announces Leadership Changes

    Eli Lilly and Company (NYSE: LLY) has announced several changes to the company's executive committee. Mike Harrington is retiring from his positions of senior vice president and general counsel at the end of the year. Senior vice president and president of Lilly Bio-medicines, Christi Shaw, is leaving Lilly at the end of August, and will be succeeded by current president and general manager of Lilly Japan, Patrick Jonsson. 

  • The official mission patch for the group. (image courtesy of Indiana University)

    IU Team Continuing Bone Study in Space

    A team of researchers from the Indiana University School of Medicine in Indianapolis will Tuesday begin the second phase of an experiment heading to space. The research project will study the effect of spaceflight on osteoblast cells, which are essential to bone development, as well as the effects of certain drugs on bone healing. Melissa Kacena, director of basic and translational research at the school, is leading the effort in collaboration with NASA and the U.S. Army. The first...

  • (photo courtesy of Catalent)

    Catalent to Break Ground on Expansion

    State and local officials will Friday join executives from New Jersey-based Catalent Inc. (NYSE: CTLT) to break ground on a new drug product manufacturing facility in Bloomington. The project is part of a $100 million expansion announced in January that is expected to create up to 200 jobs by the end of 2024.

  • Webber's lab wants to invent a material that could sense blood glucose and deliver glucagon if needed. (Photo courtesy: Notre Dame)

    $1.6M Boosts New Technologies for Hypoglycemia

    Caring for a child with type 1 diabetes is a heavy burden for parents and not limited to the daily grind of tracking blood sugar and dosing insulin; for many, the weight of worry is far greater. 

  • The microscope will sit on top of a 12-inch thick “floating” concrete platform.

    $9M Microscope Advances Scientists Statewide

    Twenty-six extremely fragile crates—including one that must remain in a vacuum—will soon be shipped from the Netherlands. Their destination: the Purdue University campus, where the contents will be pieced together to form a state-of-the-art $9 million microscope. 

  • Ostojic earned a $1,000 college scholarship as part of the award.

    Munster Teen With 2 Patents & Forbes Ranking, Earns Governor STEM Award

    A quick glance at Annie Ostojic’s Facebook page is evidence that she isn’t your average teenager—it sings of impressive scientific conquests: pictures of her when she was named to Forbes 30 Under 30 (when she was only 15), World’s 50 Smartest Teens, and shows Ostojic under the spotlight, presenting centerstage at national conferences. 

  • Paczesny is focusing on a method involving “checkpoint molecules.”

    $4.1M ‘Cancer Moonshot’ Grant Powers IU Researcher

    Immunotherapy is described as a revolution, uncovering cures for a variety of cancers. Most of the progress has benefited adults battling the disease, but a recent $4.1 million Cancer Moonshot grant is helping a Hoosier researcher extend the power of immunotherapy to children and adolescents. 

  • (photo courtesy of BioCrossroads)

    Life Sciences Growth Key for New BioCrossroads CEO

    The incoming chief executive officer of BioCrossroads says she hopes to continue the growth Indiana's life sciences sector. Patty Martin, who was announced today as the new president and CEO of the state's life sciences initiative, comes with more than two decades of experience at Indianapolis-based Eli Lilly and Co. (NYSE: LLY). She says she initially plans to spend time getting to know many of the people involved in the sector from the corporate, academic and philanthropic levels...

  • Lilly Exec Named BioCrossroads CEO

    After a national search, BioCrossroads has announced Patty Martin will become the life science initiative's next president and chief executive officer. Martin, who most recently served as chief operating officer for Lilly Diabetes, will begin her new role Monday. She will become just the third CEO in the organization's 17-year history, and succeeds David Johnson, who in December announced plans to step down from the role to serve as president and CEO of the...

  • (Image courtesy of Zimmer Biomet)

    Zimmer Biomet Announces CFO Succession Plan

    Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) has announced a succession plan for retiring Executive Vice President and Chief Financial Officer Daniel Florin. He is set to retire on July 1 and the company has announced Suketu Upadhyay has been appointed to succeed Florin. The company says Florin will continue with the company in an advisory capacity to ensure a successful transition. 

  • Minar will step down at the end of the 2019-2020 academic year.

    Minar Touts Science Center Ahead of Stepping Down

    As Franklin College President Thomas Minar prepares to step down at the end of the 2019-2020 academic year, he says the school is well-prepared to leverage its science heritage well into the future. During an interview on Inside INdiana Business With Gerry Dick, he says the school's new $17 million Health Science Center features "the most modern science facilities imaginable." Minar, who has been the school's president since July 2015, says a fundraising campaigning topping...

  • (photo courtesy of Ignite Orthopedics)

    Warsaw Company Lands FDA Clearance

    A Warsaw-based medical device manufacturer has landed a key approval. Ignite Orthopedics LLC has received FDA clearance to market its Radial Head Arthroplasty System, marking what the company says is a "significant milestone" in its mission.

  • Topp says the glucagon technology could, ultimately, revolutionize insulin pumps (courtesy: National Institute of Diabetes and Digestive and Kidney Diseases).

    $1.4M Grant Boosts Rescue Kits to Help Diabetics

    It isn’t easy doing chemistry in a panicked state, but that’s exactly what a person must accomplish when using current hypoglycemia rescue kits, says Dr. Elizabeth Topp, a Purdue University industrial and physical pharmacy professor. 

  • A device is attached to each disposable sleeve to track patients' mobility data.

    New Compression Device Aims to ‘Squeeze’ the Competition

    A Fishers-based company says it’s creating a replacement for “one of the most universally-hated products” among surgical patients. Although detested, intermittent pneumatic compression (IPC) devices are required after the vast majority of surgeries; worn on the calf from knee to ankle, the sleeves squeeze the legs every 60 seconds, increasing blood flow to prevent clots due to immobility.

  • Niculescu has developed similar blood tests to predict suicide risk and measure pain.

    PTSD Blood Test Aims for Commercialization

    Posttraumatic stress disorder (PTSD) may seem an obvious diagnosis for combat veterans, but the condition can lurk in dark corners for others not commonly screened for it, such as victims of abuse, violence or accidents. 

  • Team Stroy won the Student Soybean Product Innovation Competition (left to right: Morgan Malm, Natalie Stephenson and Ruth Zhong).

    Plastic Straws Suck: Students Invent Soy Ones

    Amid the uproar about plastic straws—including bans or pending bans in several U.S. cities—sales for paper straws are booming. But a trio of Purdue University students has a far more disruptive idea: soy straws that are 100 percent biodegradable. 

  • BASi Swings to Quarterly Loss

    West Lafayette-based Bioanalytical Systems Inc. (Nasdaq: BASI) is reporting a fiscal second quarter net loss of $569,000, compared to net income of $66,000 during the same period last year. Despite the drop, the pharmaceutical development company saw a 60 percent increase in revenue for the quarter.

  • Covance also has a location in Evansville. (image courtesy of Covance Inc.)

    Covance Plans to Grow Indy Operation

    A subsidiary of New Jersey-based Covance Inc. is looking to grow its Indianapolis footprint. Covance Central Laboratory Services Inc. plans to invest nearly $17.5 million to expand its operations on the city's west side and add more than 200 jobs.  According to documents filed with the city, the drug development and global contract research company is looking to renovate 20,000-square-feet of existing space into a state-of-the-art trial testing laboratory and construct an...

  • FDA Approves Lilly Liver Cancer Drug

    The U.S. Food and Drug Administration has given another approval for a drug from Indianapolis-based Eli Lilly and Co. (NYSE: LLY). The approval for Cyramza is for the treatment of patients with hepatocellular carcinoma, the most common form of liver cancer.

  • (photo courtesy of WishBone Medical)

    WishBone Medical Acquires Plymouth Company

    Warsaw-based WishBone Medical has acquired a medical device manufacturer in Marshall County. Financial terms of the deal for Plymouth-based CSpine Inc. are not being disclosed, however a spokesperson for WishBone tells Inside INdiana Business no jobs will be affected.

  • Elanco is headquartered in Greenfield.

    Elanco Quarterly Profit Narrows

    Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) is reporting first quarter net income of $31.5 million, down from $72.7 million during the same period last year. Despite the drop, Chief Executive Officer Jeff Simmons says the company is seeing improved value through efficiencies and cost savings.

  • The IBRI will locate in the first building at 16 Tech, which is currently under construction.

    Indiana Biosciences Research Institute Seeking Input

    The Indiana Biosciences Research Institute has launched an initiative to measure public perception of the non-profit applied research center in Indianapolis.  You can participate in the anonymous and confidential survey by clicking here.

  • Techshot is headquartered in the Floyd County town of Greenville.

    More Techshot Equipment Arrives at Space Station

    More research equipment from Greenville-based Techshot Inc. has made its way to the International Space Station. The equipment, which launched Saturday aboard an uncrewed SpaceX cargo resupply spacecraft, contains experiment modules to be used in a Massachusetts Institute of Technology tissue chip experiment.

  • (photo courtesy Indiana University)

    LifeOmic Launches LIFE Fasting Tracker

    Indianapolis-based startup LifeOmic has created an app to help people adopt the practice of intermittent fasting. Don Brown, founder and chief executive officer, says the practice isn’t only for losing weight, but can help participants reduce risk of Alzheimer's disease and Parkinson's.  Brown, who previously founded and sold Software Artistry and Interactive Intelligence, says the idea for the LIFE Fasting Tracker came from a cloud platform he used at...

  • BASi Acquires Smithers Avanza Toxicology Services

    Bioanalytical Systems Inc. (NASDAQ:BASI) has announced its acquisition of the business unit of Smithers Avanza Toxicology Services, a contract research organization located in Maryland. The acquired business will operate as a wholly-owned subsidiary of BASi under the name BASi Gaithersburg.

  • Grieco says the grant will support testing spatial repellents at a refugee setting in Uganda. (Photo: Matt Cashore, Notre Dame)

    $33M Drives Notre Dame Mission to Eradicate Malaria

    A single sheet of plastic—much like a standard piece of paper—could be the missing piece to finally win the battle against mosquito-borne diseases that cripple the health of people in developing countries. 

  • Lilly is reporting first quarter revenue of nearly $5.1 billion.

    Lilly Reports Higher Profit, Cuts Guidance

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) is reporting net income of $4.2 billion in the first quarter of 2019, compared to $1.2 billion during the same quarter last year. The increase was driven by the spin-off of Elanco Animal Health. The drugmaker has also cut its 2019 revenue guidance to between $22 billion and $22.5 billion, due in part to expected lower revenue for Cialis and other products that have lost patent exclusivity as well as the withdrawal of cancer drug...

  • Olio says its technology streamlines communication between the surgical team and post-acute providers along the patient’s entire journey.

    National Launch, $2.5M Boost Olio

    A central Indiana man who broke his hip five years ago—then broke his other hip very recently—certainly faced a medical misfortune, but is also a testament to technology transforming patient care. 

  • FAST employees manufacture the injectable, which works with a device, to measure blood volume.

    New Data Puts FAST BioMedical ‘On the 15-Yard Line’

    Doctors in critical hospital settings make judgement calls—sometimes life or death decisions—based on information, but there’s one stat that has been notoriously difficult to obtain, says Carmel-based startup FAST BioMedical. Doctors are clamoring for a better way to determine a patient’s blood volume, an important measurement that can dictate treatment in the critical care setting. 

  • Acacia is developing a drug to treat post-operative nausea and vomiting (PONV), a common complication after surgery.

    Acacia Pharma, Outpost Medicine Shaping Startup Scene

    Life sciences experts believe Indiana’s resume of successful pharmaceutical startups sets the stage for the next generation of young companies to follow in their footsteps; among the state’s young pharma proteges are Outpost Medicine and Acacia Pharma Inc. 

  • Zimmer Biomet is headquartered in Warsaw.

    Profit Grows For Zimmer Biomet

    Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) is reporting first quarter net income of $246 million, up from $176 during the same period last year. Despite the increase, the medical device manufacturer says it saw a more than 2 percent drop in net sales, largely due to the effect of foreign currency exchange.

  • Elanco is headquartered in Greenfield.

    Elanco Makes Major Acquisition

    Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) is adding to its portfolio with a major acquisition. The company has announced plans to acquire Kansas-based Aratana Therapeutics (Nasdaq: PETX) in a deal valued at up to $245 million. In conjunction with the acquisition, Elanco has also announced the formation of a commercial team dedicated to the veterinary specialty business. Elanco says the deal would allow it to integrate the Aratana portfolio of pet therapeutics into its...

  • Eli Lilly and Co. is headquartered in Indianapolis.

    Lilly to Offload Chinese Drug Rights, Manufacturing Plant

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced plans to sell the rights in China for two of its antibiotic medicines, as well as a Chinese manufacturing facility. The deal with Eddingpharm is valued $375 million.

  • Rainer Fischer was named CEO of the IBRI in October 2017.

    IBRI Chief Steps Down, Takes New Role

    The Indiana Biosciences Research Institute has announced Chief Executive Officer and Chief Scientific and Innovation Officer Rainer Fischer has stepped down from both roles. The institute says Fischer, who came to Indianapolis in 2017, will remain as a senior executive for innovation and discovery. The IBRI did not provide a reason for Fischer's decision to step down. In his new role, Fischer will work to attract new partners for sponsored and contract research, as well as new...

  • General Manager Denis Johnson talked about the company's growth on Inside INdiana Business.

    Catalent Bullish on 'Red Hot' Sector

    When Bloomington-based Cook Group Inc. announced the sale of its Cook Pharmica unit to New Jersey-based Catalent Inc., company executives promised to "invest aggressively" in creating a leader in the rapidly-growing biologics sector. Eighteen months later, there is ample proof they meant it. Catalent has announced major expansion projects in recent months totaling $114 million in investment. Employment at the Monroe County facility, which stood at 270...

  • Scientific evidence of a service dog's impact could persuade insurance companies to begin covering the cost, which can be upwards of $25,000.  (Courtesy: David Scott, Canine Assistants)

    PU Proves Service Dogs Impact Handlers’ Psyche

    “Service dog” is the official name for the four-legged companion that assists a handler who has a physical disability—but many would argue best friend, companion or lifesaver are more accurate terms. However, the animals’ positive impact is only anecdotal and lacks validity in the world of science. 

  • Sen is developing a promising technology that reprograms skin tissue to assume the functionality of tissues or organs that are no longer working properly.

    Sen’s Research, Vision Position Indiana to Lead Regenerative Medicine

    Regenerative medicine has “crossed the chasm of impossible to possible,” says a nationally-renowned expert who is leading the charge in Indiana to trailblaze the “new horizon in medicine.” Indiana University School of Medicine (IUSM) Associate Vice President of Research Dr. Chandan Sen believes the new frontier will dominate the practice of medicine within a decade. 

  • Epogee most recently earned FDA approval for a version of its fat replacement designed for fried foods.

    $8M Investment Boosts Diet-Friendly Foods

    Sweet treats and fried foods that are low in fat and calories may seem a dieter’s dream, but that’s Indianapolis-based Epogee’s mission, and it’s now backed by millions. The startup recently earned an $8.3 million investment from HG Ventures, also based in Indianapolis. 

  • Mundra says research projects like his help teach pharmacy students about drug delivery science.

    Manchester Pharmacy Claims Another Research Grant

    For the second year in a row, a Manchester University faculty member has claimed a national award that recognizes early-career researchers’ discoveries in the laboratory. 

  • Zimmer Biomet is based in Warsaw.

    Zimmer Biomet System Lands FDA Clearance

    Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) has received clearance from the U.S. Food and Drug Administration for its ROSA ONE Spine System. The system is used for robotically-assisted, minimally-invasive and complex spine surgeries.

  • Brian Dixon is the director of public health informatics for the Regenstrief Institute.

    Startup Day Brings Federal, Local Officials Together

    Local, state and federal leaders gathered at the Regenstrief Institute in Indianapolis this week to discuss innovations in healthcare and technology in Indiana. Indiana Startup Day included remarks from Ed Simcox, chief technology officer for the U.S. Department of Health and Human Services and also spotlighted seven Indiana healthcare startups. Brian Dixon, director of public health informatics for the Regenstrief Institute, says the goal of the event was for federal officials...

  • Picture Courtesy: American Cancer Society

    ResearcHERS to Boost Women Fighting Cancer

    Indiana is taking part in an American Cancer Society effort looking to fuel women-led cancer research. ResearcHERS: Women Fighting Cancer aims to raise funds to support women researchers and boost programs to inspire the next generation of girls to pursue science careers. Organizers say they are looking for "ambassadors" to help meet the goal of raising $160,000 in the inaugural year of the program. Campaign co-chair Jill Geer, who is chief marketing officer at the American...

  • The company is not committing to any new jobs as part of the project.

    Lilly Seeks Tax Abatement on $90M Project

    Indianapolis-based Eli Lilly and Co. (NSYE: LLY) is seeking a nearly $10 million tax abatement for a $90 million project to build and equip a facility to house insulin research and production. A City-County Council committee Monday approved the proposal, with a full council vote set for next week. The company is not committing to any new jobs as part of the project. Lilly says the project will allow it to keep up with peak and backup capacity demands for insulin products.

  • BioCrossroads says 2018 was a record-breaking year for venture capital investment in the sector.

    Life Sciences Workforce, Wages Increase

    Indiana's life sciences initiative is boasting a strong 2018 for the sector, reporting year-over-year increases in areas including workforce, wages, exports and venture capital funding. BioCrossroads says the state's life sciences industry's economic impact is now at $79 billion. The report shows the sector supports more than 56,000 jobs in the state with an average annual wage of over $97,000. Vice President of Communications Lori LeRoy says Indiana "maintains (its) standing as...

  • Mark Throdahl is CEO of OrthoPediatrics. (photo courtesy Nasdaq)

    OrthoPediatrics Loss Widens, Despite Record Revenues

    Warsaw-based OrthoPediatrics Corp. (Nasdaq: KIDS) is reporting a full-year net loss of $12 million in 2018, compared to a loss of $8.9 million the previous year. Despite the drop, the pediatric medical device manufacturer says it hit record revenue for the year.

  • Arun Giridhar is the co-founder and CEO of Pinpoint Pharma.

    Hoosier Startup Growing in West Lafayette

    A West Lafayette-based startup has announced plans to scale its Indiana operations. Pinpoint Pharma, which specializes in custom compounded medication for pets, says it will invest $240,000 in lease, renovate and equip new lab space in the Tippecanoe County city and create up to 27 jobs over the next few years.  Pinpoint Pharma is one of the first five Hoosier startups to take part in the gBETA accelerator program. The Indiana Economic Development Corp. says the company...

  • The drug received FDA approval for migraine treatment in September.

    Lilly Granted Priority Review For Headache Treatment

    Indianapolis-based Eli Lilly and CO. (NYSE: LLY) says one of its headache treatments is moving closer to approval. The U.S. Food and Drug Administration has granted Priority Review for a drug to be used for the preventative treatment of episodic cluster headache in adults.

  • Lilly to Roll Out Lower-Priced Insulin

    In response to ongoing pressure from Congress regarding the cost of insulin, Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced plans to roll out a lower-priced version of its insulin product Humalog. The company says the authorized generic version will have a list price 50 percent lower than the current Humalog price. Lilly says it is working to make Insulin Lispro available in pharmacies "as quickly as possible." It says a single vial will list at...

  • The single Minka house could possibly lead to a community of tiny houses near USI. (Courtesy: USI Center for Healthy Aging and Wellness)

    USI Tiny House To Develop ‘Aging in Place’ Technology

    A new “tiny” house on University of Southern Indiana’s campus is addressing some big issues associated with aging. Could elders live independently—and with better quality of life—in a compact house equipped with smart home technology? 

  • A Catalent employee inspects a vial.

    300 Vials Per Minute: The Pace of Progress for Catalent

    Just 18 months after entering Indiana’s life sciences landscape, Catalent says the “red hot” biologics sector is driving the company’s repeated large investments in Bloomington. 

  • The academy will be able to produce up to 30 of these specially trained professionals each year.

    More Workers to Wage War Against Opioid Epidemic

    Hoosiers in the grip of substance use disorder—especially related to opioids—have faced a shortage of professionals they can turn to for help, but a new project aims to produce more dually licensed clinical social workers specifically trained to battle Indiana’s opioid epidemic. 

  • Solinftec says hardware, such as computers on-board farm equipment, analyze information to help farmers “use the data better.”

    Sugarcane to Corn: Brazil Company Tweaks Technology for U.S.

    Brazil-based Solinftec may be new to Hoosier soil, but it’s already harvesting accolades in the U.S.; national agriculture media outlet Successful Farming recently named it one of “8 Ag Tech Startups Worth Watching in 2019.” 

  • (photo courtesy of Bayer)

    Bayer to Close Mishawaka Facility

    Germany-based pharmaceutical company Bayer has announced plans to close its customer logistics service center in Mishawaka. The company says the closure will take place over an 18-month transition period and will affect nearly 200 employees.

  • Lilly Completes $8B Acquisition

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has completed its $8 billion acquisition of Loxo Oncology Inc. (Nasdaq: LOXO) in Connecticut. Loxo Chief Executive Officer Josh Bilenker says the deal will allow the company to realize the full value of its pipeline of medicines.

  • BASi Profit Falls Despite Revenue Jump

    West Lafayette-based Bioanalytical Systems Inc. (Nasdaq: BASI) is reporting a fiscal first quarter net loss of $85,000, compared to net income of $26,000 during the same period the previous year. Despite the drop, the company says quarterly revenue increased more than 60 percent.

  • Russ Fellows is the project manager for Roche Academy.

    Roche Academy Aims to Fill Need For Talent

    The University of Indianapolis and Roche Diagnostics are partnering on an effort to fill a talent gap. The first cohort for Roche Academy has begun and the university says the goal is to solve the talent pipeline for biomedical equipment technicians. The academy provides a customized curriculum for the cohort of eight students, as well as a summer internship, that provides real-world training to prepare students for high-demand positions at Roche.

  • Elanco went public in September 2018.

    Lilly Reveals Plan to Offload Elanco Stock

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced plans to divest its remaining interest in Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN). The pharmaceutical giant retained a more than 80 percent ownership interest in Elanco, following the company's Initial Public Offering in September.

  • Cook Group in Bloomington is one of the largest life sciences companies headquartered in the state.

    Georgia Woman Wins $3M Verdict Against Cook Medical

    A federal jury in Indianapolis has awarded $3 million to a Georgia woman who claimed an intravenous filter made by Bloomington-based Cook Medical was defective. Tonya Brand says she suffered medical complications after the filter deteriorated inside her body.

  • Lilly says quarterly revenue increased 4.5 percent to $6.4 billion.

    Lilly Returns to Profit

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) is reporting fourth quarter net income of $1.1 billion, compared to a loss of $1.7 billion the previous year, when earnings were impacted by U.S. tax reform. The company is also cuttings its revenue and profit forecast for 2019, due in part to disappointing results from a Phase 3 study of cancer drug Lartruvo. Lilly says quarterly revenue increased 4.5 percent to $6.4 billion, topping estimates. The company cites higher sales of...

  • (image courtesy of the IU School of Medicine)

    IU Med School Hits Record NIH Funding

    Researchers at the Indiana University School of Medicine received a record amount of funding from the National Institutes of Health in 2018. The school says nearly $150 million was awarded, marking a 10 percent increase over the previous year.

  • Rehab Medical Merges With Wound Care Company

    Indianapolis-based Rehab Medical Inc. has announced a merger with medical device manufacturer Cork Medical, also based in Indy. Financial terms of the deal are not being disclosed, however Rehab Medical tells Inside INdiana Business it plans to add 50 jobs by the end of the year.

  • Lilly Acquisition Moving Forward

    Indianapolis-based Eli Lilly and Co.'s (NYSE: LLY) $8 billion acquisition of Loxo Oncology Inc. (Nasdaq: LOXO) has cleared its first hurdle. Lilly says the deal has made it past the waiting period under the Hart-Scott-Rodino Antitrust Act. The acquisition was first announced in early January. Lilly says the deal will add precision medicines to its oncology portfolio.

  • Indiana's medical device industry is widely known as one of the strongest in the world.

    Zimmer Biomet Swings to Huge Loss

    Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) is reporting a fourth quarter net loss of $903 million, compared to net income of $1.2 billion during the same period the previous year. The medical device manufacturer says the loss included goodwill impairment and litigation charges.

  • Crew Engineer Kasey Hilton points to a rock she collected for crew geologist Ellen Czaplinski.

    Purdue Students Move To ‘Mars’ For Two Weeks

    A team of six Purdue University students and alumni is readjusting to life on planet Earth after spending two weeks on “Mars.” Although they didn’t travel to the real Red Planet, the crewmembers lived in isolation inside a small research station in a remote area of Utah.

  • The test involves connecting the horse's airways to two different tanks; one with positive pressure and the other with negative (like a vacuum).

    Purdue Asthma Test Helps Heal Racehorses

    Indiana is the only place in the world with a cutting-edge respiratory testing device for horses. Veterinarians and engineers at the Purdue University College of Veterinary Medicine developed the tool to bring clarity to an elusive condition. 

  • IU Philanthropic Venture Fund Wraps First Year of ‘Perpetual’ Model

    The Indiana Philanthropic Venture Fund (IU PhV) is on the doorstep of its one-year anniversary and, although not limited to the life sciences, it has funneled $1.6 million into the sector’s early-stage Indiana-based companies. 

  • The InCore Lapidus System, an orthopedic device for the foot, contributed to sales momentum in 2018.

    Nextremity Touts Success With New Strategy

    Warsaw-based Nextremity Solutions, Inc. says 2018 was a critical year of validation. The orthopedic company changed its business model in 2016—moving away from its roots as a traditional startup and becoming a strategic commercialization organization. 

  • Life Sciences Company Makes Acquisition From Silicon Valley

    Indianapolis-based Beckman Coulter Life Sciences is adding to its portfolio. The company has acquired California-based liquid handling company Labcyte, though financial details were not immediately disclosed. 

  • IBRI is one of many life science organizations to collaborate for the new app

    IBRI Project Leads to Disease Discovery

    A collaborative research project involving the Indiana Biosciences Research Institute has led to the discovery of a new disease. The IBRI says the monogenic disease, known as DHPS Deficiency, can lead to neurodevelopmental delay and seizures. 

  • This is Eli Lilly and Co.'s first appearance on the list.

    Lilly 'Disappointed' by Cancer Drug Study

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced what it calls disappointing results of a study of a new cancer drug. The pharmaceutical giant says the Phase 3 study of Lartruvo, which aims to treat patients with advanced or metastatic soft tissue sarcoma, did not meet its primary endpoints.

  • As part of its response, Cook realigned the company's business into two divisions.

    Cook Medical Partnering on Snoring Device

    Bloomington-based Cook Medical has announced a sales and marketing agreement with Zelegent Inc. in California. Cook says the partnership aims to enhance treatment options for patients suffering from snoring.

  • Lilly's acquisition is the latest in an effort to strengthen its cancer treatment portfolio.

    Lilly Announces $8B Acquisition

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced an $8 billion deal to acquire Loxo Oncology in Connecticut. Lilly says the deal adds precision medicines to its oncology portfolio through Loxo's pipeline of medicines for patients with certain types of cancers. The Indy drugmaker says the acquisition would be the largest in its ongoing effort to strengthen its cancer treatment portfolio. Loxo's pipeline is focused on cancers that involve single gene abnormalities that can...

  • (photo courtesy of Sentry BioPharma Services)

    Commission OKs Two Indy West Side Projects

    The Indianapolis Metropolitan Development Commission has approved tax abatement for two projects on the city's west side totaling nearly $11.5 million. According to documents filed with the city, the developments would create and retain nearly 60 jobs. Indianapolis-based Sentry Ventures LLC is planning to invest nearly $9 million to build and equip a 30,000-square-foot addition to its existing facility and Japan-based Ryoei USA Inc. is looking to invest $2.5 million to build a...

  • (Image courtesy of Endocyte)

    Endocyte Shareholders Approve Acquisition

    The shareholders of West Lafayette-based Endocyte Inc. (Nasdaq: ECYT) have approved the previously-announced $2.1 billion acquisition agreement with Switzerland-based pharmaceutical company Novartis AG. The company says the deal is expected to close Friday.

  • BASi Swings to Full-Year Loss

    West Lafayette-based Bioanalytical Systems Inc. (Nasdaq: BASI) is reporting a fiscal full-year net loss of $194,000, compared to net income of $884,000 the previous year. The company says the results are due in part to one-time costs associated with its July acquisition of Missouri-based Seventh Wave Laboratories LLC.

  • A Notre Dame researcher suspects firefighters' protective clothing sheds chemicals that are linked to cancer. (photo courtesy: International Association of Fire Chiefs)

    The Mystery of Cancer in Firefighters: Two Indiana Researchers Uncover Clues

    There’s a lot of conjecture about cancer in the world of firefighting, but a crescendo of anecdotal—and scientific—evidence is driving two Indiana researchers to search for answers. 

  • Ladisch and Purdue PhD student Jessica Zuponcic (left) say the instrument could catch elusive bacteria that sneak through current methods.

    Purdue Method Could Keep Lettuce Safe

    Romaine has returned to store shelves after a recent E. coli outbreak stopped salads at both grocers and restaurants. Science is partly to blame; the U.S. Food and Drug Administration (FDA) recalled all romaine as a broad safety measure, because detecting pathogens such as E. coli takes time in the lab—up to three days in some cases. 

  • CEO Ponsi Trivisvavet says Inari aims to revive plants' natural genetic diversity that has been "lost in the system."

    Inari Chooses Indiana to Help Build Better Seeds

    ‘How do we feed 9 billion people by 2050?’ is a common rallying cry—and foreboding challenge—within the agricultural community. But a young company from the Boston area—now opening its next operation at Purdue Research Park in West Lafayette—says the right question to ask is, ‘How do we feed the world without destroying the planet?’ 

  • The company is projecting 2019 revenue between $25.3 billion and $25.8 billion.

    Lilly Issues 2019 Guidance

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced 2019 financial guidance, with projected revenue and adjusted profit above analyst expectations. The company says the growth is driven by demand for newer medicines including Trulicity, for diabetes, and psoriasis drug Taltz. The company is projecting 2019 revenue between $25.3 billion and $25.8 billion, and earnings per share between $5.52 and $5.62. Chief Executive Officer David Ricks says, while he's happy with...

  • This is Eli Lilly and Co.'s first appearance on the list.

    Lilly Acquires Pre-Clinical Program

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced an agreement with Massachusetts-based Hydra Biosciences. The company says it has acquired all assets related to a pre-clinical program from Hydra, though financial terms of the deal are not being disclosed.

  • BioCrossroads Looking to the Future During Transition

    The incoming interim president and chief executive officer of BioCrossroads says the transition in leadership will be a smooth one. The state's life science initiative announced Wednesday longtime CEO David Johnson is leaving to continue his role as CEO of the Central Indiana Corporate Partnership on a full-time basis. Norah Doherty will assume the interim position at the beginning of the year and says BioCrossroads continues to look to the future.

  • 16 Tech says the anchor building will ultimately house about 400 employees.

    Work Begins on 16 Tech's First Building

    16 Tech developers have officially broken ground on the innovation district's first building, marking the beginning of an ambitious 10-year project. The $30 million Advanced Research and Innovation building is fully-leased and will anchor the 60-acre development. The facility, which will house the Indiana Biosciences Research Institute, Central Indiana Corporate Partnership and Indiana University School of Medicine researchers, is set to be complete in mid-2020.

  • David Johnson is the CEO of the CICP and its subsidiary, BioCrossroads.

    BioCrossroads CEO Moving On

    The chief executive officer of the state's life sciences initiative is stepping down. BioCrossroads says David Johnson, who has led the organization for 14 years, is leaving at the end of the year to serve as president and CEO of the Central Indiana Corporate Partnership on a full-time basis. The CICP is the parent organization of Indiana's six talent and industry sector initiatives, including BioCrossroads. Johnson was elected president and CEO of the CICP in 2012 and has since led...

  • Mark Throdahl is CEO of OrthoPediatrics. (photo courtesy Nasdaq)

    OrthoPediatrics Making Stock Offer

    Warsaw-based OrthoPediatrics Corp. (Nasdaq: KIDS) has begun a public stock offering. The pediatric medical device manufacturer is looking to raise up to nearly $47 million as a result of the offering, which is expected to close Tuesday.

  • IBRI is one of many life science organizations to collaborate for the new app

    Notre Dame, IBRI Form 'Strategic Alliance'

    The University of Notre Dame has signed a strategic alliance agreement with the Indiana Biosciences Research Institute in Indianapolis. The IBRI says the agreement will enable both parties to "work together on research covering significant health issues in Indiana and around the world."

  • BioCrossroads Receives Fairbanks Foundation Grant

    BioCrossroads' educational efforts have received a boost from a grant from the Richard Fairbanks Foundation. The organization received a $1.48 million grant to advance opportunities in Indiana's life sciences and healthcare sectors.

  • (photo courtesy of Catalent)

    Catalent Expanding in Bloomington

    New Jersey-based Catalent Inc. (NYSE: CTLT) has announced plans to grow its Bloomington operations. The company says it will invest nearly $14 million to expand its biologics packaging capacity at its Monroe County manufacturing facility and create 36 jobs. Catalent entered the Bloomington market in 2017 with its $950 million acquisition of Cook Pharmica. The company says it will construct a 15,000-square-foot addition that will include...

  • Rick Sasso (photo courtesy of Indiana Spine Group)

    Indiana Surgeon Wins $112M Verdict

    A jury in Marshall County has awarded what is being called one of the largest verdicts in Indiana history to an Indianapolis spine surgeon and inventor. Rick Sasso would receive more than $112 million in royalties and interest which he claimed he was owed by Minnesota-based medical device company Medtronic PLC (NYSE: MDT).

  • The Apple Watch will track time spent sitting or standing, number of steps and even heartrate.

    Hoosiers Help Test Apple Watch For Joint Replacement Recovery

    The Apple Watch is no longer just a fitness tracker—a new app developed by Warsaw-based Zimmer Biomet Holdings, Inc. is like “a live-in physical therapist,” says one Hoosier orthopedic surgeon. 

  • Mills says more than 500 of the modified bandage kits have been distributed in Kenya.

    Purdue Alum Creates Bandages to Save Lives in Kenya

    A skin infection called Kaposi Sarcoma—easily treated in the U.S.—claims about one million lives each year in Kenya. The situation puzzled a Purdue University pharmacy alum and motivated him to create a medicated bandage that is now being used in the African nation. 

  • Lafontant says DePauw’s small size will provide students more hands-on time with the equipment, which the school is ordering now.

    DePauw Gets Microscopes ‘Schools Like DePauw Don’t Have’

    Powerful imaging equipment typically found at major research institutions will soon be part of the  DePauw University campus. The school is purchasing a handful of cutting-edge light and electron microscopes.

  • Conley says AcceLINX leverages the resources in the region to help entrepreneurs and early-stage companies be successful.

    AcceLINX Boosting Ortho Innovators

    The Orthopedic Capital of the World is already unique as home to the highest concentration of resources for the design, development and manufacturing of musculoskeletal products in the world—but local leaders say the region’s approach to innovation is also one-of-a-kind. 

  • Carter Cliff is the CEO of Vascugen. (photo courtesy of Indiana University)

    IU Fund Makes Another Medical Investment

    The Indiana University Philanthropic Venture Fund has announced support for an Indianapolis-based regenerative medicine company. While specific numbers are not being released, the fund says it has invested in Vascugen Inc., which focuses on finding therapies to repair human tissue damaged by reduced blood flow due to disease or injury.

  • NICO Corp. makes a variety of neurosurgical devices.

    Medical Device Company Secures $12.5M in Funding

    Indianapolis-based NICO Corp. has completed a $12.5 million Series B round of funding. The neurosurgical medical device manufacturer says the funding will support a variety of priorities, including new product development and commercialization, as well as additional clinical studies.

  • Indiana Attorney General Curtis Hill

    State Files Suit Against Pharmaceutical Company

    Indiana Attorney General Curtis Hill has filed suit against a Connecticut-based pharmaceutical manufacturer. The lawsuit alleges Purdue Pharma, which makes opioid products such as OxyContin, played a key role in the state's opioid crisis by misrepresenting the risks and benefits of opioids.

  • (Image courtesy of Endocyte)

    Endocyte Loss Narrows Amid Pending Acquisition

    West Lafayette-based Endocyte Inc. (Nasdaq: ECYT) is reporting a third quarter net loss of $12.6 million, compared to a net loss of $23.3 million during the same period a year earlier. The biopharmaceutical company is in the midst of a proposed $2.1 billion acquisition by Switzerland-based Novartis AG, which is expected to close in the first half of next year. The deal is considered the largest of its kind ever for an Indiana life sciences company.

  • IBRI is one of many life science organizations to collaborate for the new app

    IBRI Details Medical Data Collaboration

    The Indiana Biosciences Research Institute in Indianapolis has announced a partnership with a global information technology consulting company. Massachusetts-based Virtusa Corp. (Nasdaq: VRTU) says the collaboration will involve analyzing synthetic medical data, which isn't subject to the same privacy regulations as real-world data sets, to accelerate research on diseases like diabetes. The collaborative analyses, IBRI and Virtusa say, will use...

  • (Image courtesy of Indiana University.)

    Don Brown to Headline Life Sciences Presentation

    One of the biggest names in the state's technology scene will deliver a keynote address Friday at a life sciences industry event. Don Brown, who founded and sold Software Artistry and Interactive Intelligence and launched a third company in 2016, LifeOmic, will headline The Changing Business of Healthcare conference at the Roche Diagnostics corporate headquarters in Indianapolis. The event is part of...

  • The foundry spans 26,000 square feet in the Purdue Research Park.

    Cambridge Ag Company Picks Purdue Research Park

    A Boston-based seed development and plant breeding company is expanding into the Purdue Research Park. Inari will open what it calls the world's first Seed Foundry at the complex. The company says the work done there can help "revolutionize the seed industry" and create a more resilient and sustainable food system. Inari Senior Vice President of Operations Mark Stowers says the 26,000 square-foot facility will ultimately house about 50 people, but adds there is plenty...

  • (Image courtesy of Ivy Tech Community College.)

    Dozens of Employers to Attend Fort Wayne Job Fair

    Nearly 70 employers are expected to attend a jobs event Wednesday in northeast Indiana. Ivy Tech Community College Fort Wayne is hosting the 2018 Fall Career Fair, which is open to the public and will feature opportunities to talk with companies in fields including heath care, manufacturing and nonprofit. In addition to meeting with employers, Ivy Tech says the event will include free professional headshots for jobseekers to use on LinkedIn profiles. Employers expected to be in...

  • Lilly Reports Higher Earnings

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) is reporting third quarter net income of $1.42 billion, compared to $1.1 billion during the same period last year. The report is the pharmaceutical maker's first since Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) spun out as an independent company. Chief Executive Officer David Ricks characterized the results as strong and adding revenue guidance was increased. For the full year, Lilly expects revenue to be...

  • Elanco says third quarter revenue hit $761.1 million, a 9 percent increase over last year.

    Elanco Swings to Profit in First Post-IPO Earnings

    Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) is reporting its first set of earnings since spinning off from Eli Lilly and Co. (NYSE: LLY) earlier this year. The company is reporting third quarter net income of $60.2 million, compared to a loss of $20.7 million during the same quarter last year. Elanco says revenue hit $761.1 million for the third quarter, which is a 9 percent increase compared to the third quarter of 2017. The company credits a...

  • Lilly says it has made a $15 million equity investment in NextCure.

    Lilly, Maryland Company Ink $40M Partnership

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has entered into a multiyear partnership with NextCure Inc. in Maryland. As part of the at least $40 million deal, the companies will work together on immuno-oncology therapies through NextCure's FIND-IO platform. NextCure will receive $25 million from Lilly upfront, and will be eligible for milestone and royalty payments if Lilly can develop and commercialize new cancer therapies through the collaboration. The Indianapolis company has...
  • BioCrossroads awarded Regenstrief Institute (left) top prize. DigiBiomarkers' technology (right) won second place.

    First ‘Inject Tech Challenge’ Crowns Winners

    Digital technology is defining the future for Indiana’s life science companies, say local leaders. The state’s life sciences initiative BioCrossroads is fanning the flame of entrepreneurs dreaming up the digital health solutions of tomorrow. 

  • Anderson 'Perfect Environment' For Italpollina Operation

    The head of an Italian agbiosciences company that has established its North American headquarters in Anderson calls Indiana "the perfect environment for business." During a ribbon cutting ceremony Friday on a former General Motors plant site, Italpollina Chief Executive Officer Luca Bonini said his company is already working on a second production phase that could open the door for exports from the Madison County operation. The company now has...

  • Elanco is headquartered in Greenfield.

    Elanco Partners With Danish Company

    Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) has announced a global research and development partnership with Denmark-based Novozymes A/S. Elanco says the collaboration aims to develop nutritional health products for beef cattle and dairy cows throughout the world.

  • (Images of Luca Bonini, Susan Wasson and Brian Emerick supplied by AgriNovus Indiana.)

    Agbiosciences Leaders Join AgriNovus Indiana Board

    AgriNovus Indiana has added three to its board of directors. Chief Executive Officer Beth Bechdol says the new board members represent a diverse mix of backgrounds and industries within the agbiosciences sector. The new board members are...

  • Joe Wheat founded MiraVista in 2002.

    Diagnostics Developer Plans Indy HQ Expansion, Jobs

    Indianapolis-based MiraVista Diagnostics LLC has announced a $5.3 million expansion. The fungal disease testing company says it plans to add up to 31 jobs by 2021 and double the size of its headquarters. MiraVista currently employs 44 and says hiring is expected to begin next year for positions including customer service representatives, laboratory technicians, research scientists and sales and marketing associates. The new positions are expected to pay...

  • Venture Winners Take Aim at Diabetes, Disease Outbreaks

    Patients who have undergone a diabetes-related amputation currently face a terrifying prognosis: only 50 percent survive one year after the procedure. Notre Dame startup SalvePeds believes it has uncovered a drug that will save the limbs and lives of people with diabetes. Purdue University startup OmniVis also aims to save lives by battling disease outbreaks in low-resource areas. 

  • Mend Medical executive team (left to right): Bryce Isch, Ben Joseph and Seth Nash.

    Investment Firm Aims to ‘Mend’ Healthcare Industry

    A unique investment firm in Fort Wayne dedicated to “healing healthcare” is now open for business—with a special focus on northern Indiana. 

  • Nallathamby and his team are developing a double-sided nanoparticle.

    Researcher Tweaks T-Cells for Tumors

    A new cutting-edge cancer treatment called CAR T-cell therapy—which requires only a single treatment—is curing patients with certain lymphomas and blood cancers, but researchers are struggling to translate the treatment for solid tumors. 

  • Katherine Pawelczak is vice president for research at NERx Biosciences. (photo courtesy of Indiana University)

    IU Fund Invests in Drug Company

    The Indiana University Philanthropic Venture Fund has announced plans to invest $500,000 in an Indianapolis-based drug development company. NERx Biosciences says the investment will further development of its first-in-class targeted cancer therapy drug. 

  • (Image courtesy of Lilly)

    Lilly Details Collaboration That Could Grow Exponentially

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced a $100 million global licensing and research collaboration. The company will partner with Massachusetts-based Dicerna Pharmaceuticals Inc. (Nasdaq: DRNA) on potential cardio-metabolic disease, neurodegeneration and pain treatments. The deal also involves a $100 million equity investment from Lilly. More than 10 targets are expected to be involved. Lilly says Dicerna could receive...

  • Indiana's medical device industry is widely known as one of the strongest in the world.

    Profit Jumps For Zimmer Biomet

    Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) is reporting third quarter net income of $162 million, up from $98.8 million during the same period last year. Chief Executive Officer Bryan Hanson says the earnings reflect the company's sustained progress in a number of areas. 

  • Program Offers Rehab to Workers Who Fail Drug Test

    As opioid addiction issues continue to ravage Hoosier communities and the workforce, a global manufacturer with multiple Indiana locations is offering rehabilitation assistance for potential employees who fail pre-hiring drug screenings. Belden, which has had a longtime presence in Richmond, has launched Pathways to Employment in response to a tripling of drug test failures and an ongoing need for talent. VP of HR Leah Tate says more than two-thirds of participants are still with it.

  • Cook Regentec Focused on Breakthroughs, Collaboration

    Bloomington-based Cook Regentec has opened its first facility in Indianapolis. The company has transformed an old beer warehouse into space at the high-profile 16 Tech innovation district. Part of the space will be dedicated to what the regenerative medicine therapy incubator and accelerator is calling The Collaboratory, where its scientists, engineers and product developers will partner with Indiana University School of Medicine researchers.

  • (Image provided by Lilly.)

    Positive Studies Push Promising Lilly Treatment Forward

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has announced a key potential treatment is moving closer to market. Taltz, which is being tested for use by patients with a type of arthritis that causes inflammation in the spine, has met its targets on two late-stage studies. Lilly says the positive results clear the way for it to submit the ankylosing spondylitis treatment for U.S. regulatory approval later this year. VP of Immunology Development Lotus Mallbris says...

  • BASi Begins Mount Vernon Expansion

    West Lafayette-based Bioanalytical Systems Inc. (Nasdaq: BASI) has broken ground on the expansion of its GLP toxicology facility in Mount Vernon. The company says the project will more than double the facility’s current capacity.

  • Mark Throdahl is CEO of OrthoPediatrics. (photo courtesy Nasdaq)

    OrthoPediatrics Lands FDA Clearance

    Warsaw-based OrthoPediatrics Corp. (Nasdaq: KIDS) has received clearance from the U.S. Food and Drug Administration for its newest surgical system. The company says the RESPONSE System is designed to treat smaller stature young patients with complex scoliosis. 

  • DowDuPont Paints Picture of Ag Spin-Out

    Michigan-based DowDuPont Inc. is providing a detailed look at the scope of its agriculture spin-out Corteva Agriscience. The independent company, which will have a significant presence in Indianapolis, will be made up of a combination of Indianapolis-based Dow AgroSciences, DuPont Pioneer and DuPont Crop Protection. The spin is expected to take place June 1. In a notice to shareholders included in a U.S. Securities and Exchange Commission filing, CEO James Collins said...

  • (Image courtesy of Endocyte)

    $2.1B Endocyte Deal a Record-Breaker

    A veteran of Indiana's life sciences industry says the proposed blockbuster sale of West Lafayette-based Endocyte Inc. (Nasdaq: ECYT) is good for the ecosystem in the state. Switzerland-based Novartis AG has signed an agreement to acquire Endocyte for $2.1 billion, which BioCrossroads Project Director Brian Stemme says is "by far" the largest-ever acquisition of an Indiana life sciences company. The deal still faces regulatory and shareholder hurdles.

  • Mike Sherman is CEO of Endocyte.

    Endocyte, Novartis Ink $2.1B Merger Agreement

    West Lafayette-based Endocyte Inc. (Nasdaq: ECYT) has announced a merger agreement with a global pharmaceutical giant. The deal with Switzerland-based Novartis AG is valued at $2.1 billion and still requires shareholder approval. Until regulatory and other approvals are met, Endocyte will remain independent. The proposed merger of Endocyte into Novartis is slated to be complete in the first half of next year. Endocyte develops targeted cancer therapies and earlier this...

  • Zimmer Biomet Partnering With Apple

    Warsaw-based Zimmer Biomet Holdings Inc. (NYSE: ZBH) has announced a partnership with Apple Inc. (Nasdaq: AAPL) to assist patients undergoing knee and hip replacement surgeries. Zimmer Biomet has developed an app for the iPhone and Apple Watch designed to improve the connection between patients and their surgical care teams.

  • Ben Forrest is CEO of Olio.

    Tech Startup Aims to Cut Out Medical 'Stumbling Block'

    As healthcare continues to evolve, a Carmel-based tech startup is rising to meet one rapidly-changing facet of the industry's business model. Olio develops software that it says helps providers at every stage of care communicate more effectively. CEO Ben Forrest says the platform his growing company has developed overcomes the traditional stumbling block of sharing information on a patient's recovery among multiple caregivers, health systems and facilities from start-to-finish.

  • Shekhar (left) and BioCrossroads CEO David Johnson (right)

    BioCrossroads Announces Watanabe Winner, New Seed Fund

    Indiana University Associate Vice President for Clinical Affairs Anantha Shekhar is the 2018 Watanabe Life Sciences Champion of the Year. BioCrossroads made the announcement today at its annual Life Sciences Summit in Indianapolis. Shekhar is leading the $120 million Precision Health Grand Challenges effort. Also at today's event, the state's life sciences initiative announced the $9 million Indiana Seed Fund III, focused on life sciences, health IT and agbiosciences companies.

  • Officials from the Regenstrief Institute accepted the first place prize in the Inject Tech Challenge. (photo courtesy of Regenstrief Institute)

    Life Sciences Summit Competition Winners Unveiled

    BioCrossroads has unveiled the winners of two competitions at the 2018 Indiana Life Sciences Summit. The events include the inaugural Indiana Inject Tech Challenge, which focuses on the creation of new technologies designed to improve patient outcomes, as well as the BioCrossroads New Venture Competition.

  • (photo courtesy of DePauw University)

    Grant to Establish Biomedical Imaging Center at DePauw

    A three-year, $527,000 grant from the Buehler Family Foundation will establish the Buehler Biomedical Imaging Center at DePauw University. The school says the center will give students access to cutting-edge equipment as they study regeneration biology, wound healing, and the neuroscience of addiction.

  • (photo courtesy of BioCrossroads)

    Life Sciences Summit to Kick Off

    Indiana's life sciences initiative will this week host its annual two-day gathering focusing on the future of the life sciences sector. The 2018 Indiana Life Sciences Summit will feature keynote addresses from representatives of industry companies such as LifeOmic, Eli Lilly and Co. (NYSE: LLY), and Roche Diagnostics.

  • A Topping Off Ceremony Takes Place Thursday Morning on the First Structure at 16 Tech

    First 16 Tech Building Fully Leased

    The first new building in Indianapolis' innovation district is fully leased. 16 Tech developers say the $30 million research and office facility will house the Indiana Biosciences Research Institute, Central Indiana Corporate Partnership and Indiana University School of Medicine researchers. Construction on the anchor facility is set to begin later this year. IBRI will take more than 67,000 square feet of space on the first three floors of the building. The institute aims to...

  • IU neurologist Liana Apostolova will lead the study. (photo courtesy Indiana University)

    IU-Led Study Lands Major NIH Grant

    A team of researchers led by an Indiana University School of Medicine neuroscientist has received the largest single grant from the National Institutes of Health. The nearly $45 million grant will fund a five-year national research study on a rare form of Alzheimer’s disease. The study is being led by IU neurologist Liana Apostolova. The Longitudinal Early-Onset Alzheimer's Disease Study, or LEADS, aims to provide a foundation that may lead to new therapies for the disease.

  • (Image courtesy of Endocyte)

    Endocyte Hits $1.5B Mark

    Purdue University says West Lafayette-based Endocyte Inc. (Nasdaq: ECYT) has become its first startup to reach $1.5 billion in value. The company says its drug platforms in various stages of development and clinical trials are showing promising results in treating conditions including advanced prostate cancer and pediatric bone cancer. Endocyte was founded in the Purdue Research Park, with most of its technology based on research by Purdue Presidential Scholar in Drug...

  • (Image courtesy of Eli Lilly and Co.)

    Lilly Migraine Treatment to Hit U.S. Market

    A preventative migraine treatment from Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has cleared a major hurdle. Emgality, a once-monthly injectable treatment, has received U.S. Food and Drug Administration approval. The pharmaceutical manufacturer says Emgality will be commercially available shortly and that a Medical Expenditures Panel Survey suggests costs in the U.S. associated with migraine total up to $56 billion a year. The disease affects 30 million adults in the country.

  • The winners will be announced at this year's Indiana Life Sciences Summit. (photo courtesy of BioCrossroads.)

    BioCrossroads Names Competition Finalists

    BioCrossroads has announced the finalists for its annual New Venture Competition and the inaugural digital health competition known as the Indiana Inject Tech Challenge. The state's life sciences initiative says the winners of both events will be announced at the 2018 Indiana Life Sciences Summit next month.

  • Frustration with the traditional inventory model during their orthopedic careers inspired RAM’s founders to  solve the problem.

    ‘Vision System’ Aims to Overhaul ‘Archaic’ Device Inventory Management

    After more than 20 years working for implant manufacturers and trying to unravel a muddled inventory system, leaders of a young Fort Wayne company believe their technology delivers a solution. 

  • Pinpoint Pharma (left) and Brightlamp are working with the Purdue Foundry to develop their technologies.

    Indiana Life Sciences Entrepreneurs Shine in Silicon Valley

    Eight Indiana-based early-stage startups took a trip to Silicon Valley to showcase Hoosier ingenuity, entrepreneurship and the state’s blossoming tech industry. The group, hosted by the Indiana Economic Development Corporation, set up shop in Startup Alley during the TechCrunch Disrupt SF Conference earlier this month in San Francisco. 

  • The school believes examining the skin disorder through an osteopathic lens will provide a unique perspective.

    First NIH Grant Boosts Marian’s Medical School

    A young medical school in Indiana is celebrating a National Institutes of Health (NIH) grant that will not only address a common skin condition, but also establish the university’s footing in nationally-recognized research. 

  • Nanovis makes nanotechnology-enhanced spinal implants.

    Indiana Investors Lead $5.5 Million Boost to Nanovis

    A Carmel-based company that says it makes “superior” spinal implants is celebrating a $5.5 million investment round and preparing to reveal its newest technology. 

  • (Image courtesy of Junior Achievement of Central Indiana.)

    Job Event For Students Aims to 'Spark' Enthusiasm

    An event this week in Indianapolis is providing over 9,000 central Indiana 8th graders with what organizers say is a first-hand look at potential future careers. JA JobSpark, an annual Junior Achievement of Central Indiana program, brings together students from 62 schools and representatives from 120 employers to take part in career exploration activities. JA of Central Indiana Chief Executive Officer Jennifer Burk says it's never too early to engage students in...

  • (photo courtesy Westgate@Crane Technology Park)

    Researchers Set For Inaugural Technology Showcase

    The Indiana Technology Showcase at the WestGate Academy will debut Tuesday in Odon. It will feature 30 researchers from the University of Notre Dame, Purdue University, Indiana University, University of Southern Indiana, Ivy Tech Community College and the Crane Naval Surface Warfare Center. Each will have three minutes to present their technologies, followed by time to discuss the innovations and potential licensing opportunities. The technology fields expected to be covered include...

  • Elanco was front and center Monday at the New York Stock Exchange. (photo courtesy NYSE)

    Elanco Rings Opening Bell at NYSE

    Officials from Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) rang the opening bell Monday at the New York Stock Exchange. The event marked the company's Initial Public Offering, which began last week.

  • (Image courtesy of IUPUI)

    Regenstrief, IU Aging Center Partner on First-of-Its-Kind Study

    Researchers at the Regenstrief Institute Inc. in Indianapolis and the Indiana University Center for Aging Research have received $3 million from the National Institute on Aging. The grant will cover five years and focus on studying the benefits and harms of Alzheimer's disease screenings for family members of likely caregivers should their older relatives be diagnosed with Alzheimer's. The institute and center say this type of research has never been conducted.

  • James Collins will be CEO of Corteva Agriscience.

    DowDuPont Announces Ag Leadership

    DowDuPont (NYSE: DWDP) has named the senior leaders for its agriculture division, which will be spun-off as a condition of the massive merger between Dow and DuPont. Corteva Agriscience, which officials say will have a significant presence at the Dow AgroSciences campus on the northwest side of Indianapolis, will be led by current ag division Chief Operating Officer James Collins. The merger of Dow and DuPont closed a year ago. Collins previously served as...

  • (Image courtesy of Elanco)

    Elanco Begins IPO

    Greenfield-based Elanco Animal Health Inc. (NYSE: ELAN) has begun its Initial Public Offering on the New York Stock Exchange. The company, which is being spun off from Indianapolis-based Eli Lilly and Co. (NYSE: LLY), is looking to raise more than $1.7 billion from the IPO.

  • (Image courtesy of WTC Indianapolis) Fahad Al Gergawi, pictured right next to Indiana Secretary of Commerce Jim Schellinger and Governor Eric Holcomb, met with business and economic leaders in Indianapolis.

    Dubai Trade Official Talks Indiana Opportunities

    An economic development official from the United Arab Emirates is using a trade mission in Indianapolis to showcase economic opportunities in Dubai. Dubai FDI Chief Executive Officer Fahad Al Gergawi said Indianapolis is one of more than a dozen U.S. cities he and his colleagues have toured in the last four years that possess "significant strength in terms of international trade." Al Gergawi estimates some $240 million in exports from Indiana maker their way to the UAE...

  • IBRI is one of many life science organizations to collaborate for the new app

    New IBRI Center to Focus on Diabetes

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) is teaming up with the Indiana Bioscience Research Institute and the Indiana University School of Medicine to create the Lilly Diabetes Center of Excellence. Lilly says the goal of the center is to establish a nexus of strategically-aligned basic diabetes research operations in Indy. The LDCE plans to recruit principal investigators to pursue cutting-edge research in diabetes, diabetic complications, and related metabolic disorders.

  • Before being loaded onto the drone, high-tech Helmer refrigerators ensure the blood stays within a very tight temperature range.

    Helmer Helping High-Tech Lifesaving Mission

    An Indiana company is playing a key role in a lifesaving mission in Africa. Noblesville-based Helmer Scientific, which makes medical-grade refrigerators, freezers and blood bank storage equipment, is working with a Silicon Valley company to deliver critical blood supplies to remote areas of Rwanda. Helmer is working with robotics company Zipline on the high-tech effort, which the Indiana company says specifically targets mothers that have bleeding issues while giving birth. During an...

  • The company's NSS-2 BRIDGE device helps to treat opioid withdrawal symptoms. (photo courtesy Innovative Health Solutions)

    Opioid Withdrawal Device Advances in Ohio Competition

    A Ripley County-based medical device company is among 12 to advance in a competition aimed at finding new solutions to combat the opioid addiction crisis. Innovative Health Solutions in Versailles has received $200,000 in funding for advancing to the second phase of the Ohio Opioid Technology Challenge.

  • Trade Officials From Dubai Heading to Indy

    A delegation of business, economic development and governmental officials from the United Arab Emirates will be in Indianapolis beginning Sunday. The visit, hosted by World Trade Center Indianapolis, will focus on boosting economic ties between the state and the Middle Eastern nation. WTC Indianapolis President Doris Anne Sadler told Inside INdiana Business international visits like this will attract additional visits. Interest in this event, she added, has already sparked...

  • (Image from Franciscan Health provided to the city of Carmel)

    Franciscan Health Eyes $130M Carmel Ortho Hospital

    Mishawaka-based Franciscan Health is planning a $130 million orthopedic hospital in Carmel. The proposed Franciscan Health Orthopedic Center of Excellence is expected to employ more than 430. The proposal is set to go before the city's plan commission September 18.

  • As part of its response, Cook realigned the company's business into two divisions.

    Cook Resolves 2014 FDA Warning Letter

    Bloomington-based Cook Medical says it has closed out the process of resolving a 2014 warning letter from the U.S. Food and Drug Administration involving documentation and data collection. Cook says the resolution is the result of "countless hours of hard work by hundreds of people" to improve its quality system. Cook Group and Cook medical President Pete Yonkman says the feedback from the FDA letter was "tough, but beneficial." As part of its response, Cook...

  • (Rendering courtesy of Ball State University.)

    Design Unveiled For Ball State Sciences Building

    Ball State University trustees have received the proposed design for a five-story, $87.5 million Foundational Sciences Building. The project, which is expected to take two years, could get underway next fall. The facility is the larger of two that will eventually replace the aging Cooper Science Complex as the primary homes of the university's science and health-based academic programs. The other piece, the $62.5 million Health Professions Building, is slated to open around...

  • Cook Biotech is located at the Purdue Research Park in West Lafayette.

    Cook Biotech Partnering with Massachusetts Company

    West Lafayette-based Cook Biotech Inc. is partnering with AcuityBio Inc. in Massachusetts to continue work on a lung cancer product. The companies say they will collaborate on the advancement of AcuityBio's ABC103, which will feature proprietary technology from Cook Biotech.

  • Elanco is headquartered in Greenfield.

    Elanco Releases Details on IPO

    Greenfield-based Elanco Animal Health Inc. has provided more details on its upcoming Initial Public Offering. The subsidiary of Eli Lilly and Co. (NYSE: LLY) has not yet released a date for the IPO, but says it will list its common stock on the New York Stock Exchange under the ticker symbol "ELAN."

  • (Image of interviewers Shannon, Dengke and Jaedyn courtesy of "State of Change.")

    Documentary to Feature Hoosier Students' Future-Shaping Journey

    A new documentary that follows the journey of three Indiana students interviewing professionals in some of Indiana's signature industries debuts Thursday. "State of Change" was produced in partnership with Roadtrip Nation, a national organization focused on career exploration. Some of the companies featured in interviews by the students include Scott Farms in Carroll and Cass counties, GE Aviation in Lafayette and Salesforce.com Inc. in Indianapolis.

  • Joseph Wallace (photo courtesy IUPUI)

    IUPUI Professor Lands $2M NIH Grant

    The National Institutes of Health has awarded a $2 million grant to an IUPUI professor. Joseph Wallace, associate professor of biomedical engineering, says the five-year grant will be used to research ways to build bone mass and improve bone quality in people with osteoporosis and diabetes.

  • White to Lead Lilly Oncology

    Indianapolis-based Eli Lilly and Co. (NYSE: LLY) has named Anne White president of Lilly Oncology. White will also serve as senior vice president for the parent company and will succeed Sue Mahony, who is retiring. White first came to Lilly in 1991 as an engineering before taking multiple clinical research and drug development positions inside and outside the company. She currently serves as...

  • (Rendering courtesy of Premier BioSource.)

    Research Swine Company Selects Jasper County

    An agbiosciences company from California has broken ground on its first Indiana operation. Premier BioSource, which raises swine for research purposes, plans to invest about $7.5 million into a 600-sow production facility in Rensselaer. The company says it considered other locations in Michigan and Illinois, but selected Indiana because of its business climate and financial strength. The operation is expected to be open within a year and employ 21 in Jasper County.

  • (Image courtesy of Roche Diagnostics.)

    Roche Academy Boasts Training, Job Offer

    Roche Diagnostics Corp. in Indianapolis, the University of Indianapolis and Ascend Indiana have announced a collaboration designed to fill high-need technical jobs at the biotechnology company. The Roche Academy will include customized curriculum and internships for UIndy biology and chemistry students which could lead to job offers from the company upon graduation. Recruiting efforts for the program are expected to begin in October and, once students complete...

  • Life Sciences Video

    • IHTC Helping Kenyans

      A person living in the U.S. diagnosed with hemophilia can still lead a normal life, but that’s not the case for patients in developing countries. The Indiana Hemophilia and Thrombosis Center is on a mission to change that for people living in Kenya, where there was little to no treatment available until the center came along.

    • Catalent Sees Growth in Emerging Biologics Sector

      A year-and-a-half after entering Indiana’s life-sciences environment, New Jersey-based Catalent says the emerging biologics sector is driving big investment in Bloomington. Catalent General Manager Denis Johnson joins us to explain what’s driving the growth and what’s next for the company.

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      India Wants to Partner with Indiana on Sports

      Indiana Secretary of Commerce Jim Schellinger says a recent trade trip to India included a rare meeting that produced some interesting results.  Schellinger and Governor Eric Holcomb were granted an audience with Indian Prime Minister Narendra Modi.  “We were taken aback at how well he knew Indiana,” said Schellinger. “He knew our (economic) background, our educational background, our history of sports statewide,” said Schellinger, who added...

    • (Image courtesy of Indiana State University)

      ISU 'Dreams' of Major Sports Facilities Improvement

      When Indiana State University developed a master plan for its campus, it didn’t include sports and athletic facilities. That’s about to change.  The university this week revealed a major plan for their sports facilities, according to a report from The Tribune Star of Terre Haute. 

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    • (Image Courtesy: Purdue Agricultural Communication)

      Slow Harvest in Indiana, Mixed Yield Estimates

      As fall harvest rolls along across the Corn Belt, the U.S. Department of Agriculture has updated its predictions of the size of the nation’s corn and soybean crops. In Indiana, the data shows the state’s corn yield has improved, while soybeans dropped over the past month. 

    • Lauren Petersen and Johna Norton

      United Way Names New Board Members

      United Way of Central Indiana has elected Lauren Petersen (pictured) and Johna Norton (pictured) its newest board members. Petersen currently serves as TechPoint’s senior director of relationship management. She graduated summa cum laude from Ball State University in 2011 where she earned a bachelor’s degree in urban planning and development. Norton serves senior vice president, Global Quality for Eli Lilly and Co.